Plate holder

• US 5,993,746 A
• Filed: 03/20/1998
• Issued: 11/30/1999
• Est. Priority Date: 09/22/1995
• Status: Expired due to Term

• Current Assignee: Labsystems Oy (Thermo Fisher Scientific Incorporated)
• Original Assignee: Labsystems Oy (Thermo Fisher Scientific Incorporated)
• Inventors: Tupakka, Heikki, Priha, Matti
• Primary Examiner(s): Le, Long V.
• Application Number:
  US09/043,710
• Time in Patent Office: 620 Days
• Field of Search: 422/104, 422/63, 422/66, 422/99, 436/46, 436/43, 436/47, 436/49, 436/165, 356/244
• US Class Current: 422/82.08
• CPC Class Codes: B01L 2300/0829 Multi-well plates; Microtitration plates
• CPC Class Codes: B01L 9/523 for multisample carriers, e.g. used for microtitration plates
• CPC Class Codes: G01N 2035/042 moved independently, e.g. by fork manipulator
• CPC Class Codes: G01N 35/028 having reaction cells in the form of microtitration plates
• CPC Class Codes: Y10T 436/11 Automated chemical analysis
• CPC Class Codes: Y10T 436/113332 with conveyance of sample along a test line in a container or rack
• CPC Class Codes: Y10T 436/114998 with treatment or replacement of aspirator element [e.g., cleaning, etc.]

Abstract

A holder for sample-holding plates has a retainer for pressing a plate placed in the holder both against the back wall and against a side wall. Thus a plate of a certain type will always settle in the same position in the holder. It is also possible to use in the holder plates of many sizes, which can be kept in place during handling owing to the retainer. The device is suitable for use in particular in assay methods in which samples to be assayed are handled on plates having a plurality of wells, for example in optical analyzers or other apparatuses.

Claims

1. A holder for a sample-holding plate defining one or more sample-holding wells, said holder comprising a back wall and a side wall and defining a space between said back wall and said side wall into which a sample-holding plate can be placed,

characterized in that

said holder further comprises a retainer mounted to a holder frame for movement relative to said space between a first position for pressing a sample-holding plate placed in said space against both said back wall and said side wall and a second position retracted from pressing the sample-holding plate, said retainer comprising an arm defining a pressing surface disposed for pressing engagement with the sample-holding plate.

2. A holder according to claim 1, further comprising a spring mounted to urge said retainer toward said first position for pressing against the sample-holding plate.

3. A holder according to claim 1, wherein said holder is mounted in a movable carrier.

4. A holder according to claim 3, wherein said moveable carrier has a specific loading position at which the sample-holding plate is placed in the space of said holder or removed therefrom.

5. A holder according to claim 4, further comprising a retainer releaser adapted to urge said retainer toward said second position retracted from pressing the sample-holding plate when the moveable carrier is in its specific loading position.

6. A holder according to claim 5, wherein said retainer releaser is a stop defining a stop surface for engagement by said retainer in said second position.

14. A holder according to claim 1, wherein a lower part of said side wall defines a support for the sample-holding plate.

15. A holder according to claim 14, wherein an edge of said holder is provided with detachable pins.

16. A holder according to claim 1, wherein said holder is adapted for use with sample-holding plates of different types.

17. A holder according to claim 1, further comprising a retainer releaser positioned to urge said retainer toward said second position, retracted from pressing the sample-holding plate.

7. An optical analyzer comprising a holder for a sample-holding plate defining one or more sample-holding wells, said holder being mounted in said optical analyzer and comprising a back wall and a side wall and defining a space between said back wall and said side wall into which a sample-holding plate can be placed,

characterized in that

said holder further comprises a retainer mounted to a holder frame for movement relative to said space between a first position for pressing a sample-holding plate placed in said space against both said back wall and said side wall and a second position retracted from pressing the sample-holding plate, said retainer comprising an arm defining a pressing surface disposed for pressing engagement with the sample-holding plate.

9. An optical analyzer according to claim 7, wherein light from a sample can be taken for measuring from either above or below said holder.

10. An optical analyzer according to claim 9, said optical analyzer further comprising an optics module selectively positionable above and below said holder.

12. An optical analyzer according to claim 7, wherein said holder is mounted in a moveable carrier having a specific loading position at which the sample-holding plate is placed in said holder or removed therefrom, and said holder further comprises a retainer releaser adapted to urge said retainer toward said second position retracted from pressing the sample-holding plate when the moveable carrier is in its specific loading position.

13. An optical analyzer according to claim 12, wherein said retainer releaser is a stop wall defined by a stop and positioned for engagement by said retainer in said second position.

8. A fluorometer comprising a holder for a sample-holding plate defining one or more sample-holding wells, said holder being mounted in said fluorometer and comprising a back wall and a side wall and defining a space between said back wall and said side wall into which a sample-holding plate can be placed,

characterized in that

said holder further comprises a retainer mounted to a holder frame for movement relative to said space between a first position for pressing a sample-holding plate placed in said space against both said back wall and said side wall and a second position retracted from pressing the sample-holding plate, said retainer comprising an arm defining a pressing surface disposed for pressing engagement with the sample-holding plate.

21. A fluorometer according to claim 8, wherein light from a sample can be taken for measuring from either above or below said holder.

22. A fluorometer according to claim 21, said fluorometer further comprising an optics module selectively positionable above and below said holder.

23. A fluorometer according to claim 8, wherein said holder is mounted in a moveable carrier having a specific loading position at which the sample-holding plate is placed in said holder or removed therefrom, and said holder further comprises a retainer releaser adapted to urge said retainer toward said second position retracted from pressing the sample-holding plate when the moveable carrier is in its specific loading position.

24. A fluorometer according to claim 23, wherein said retainer releaser is a stop wall defined by a stop and positioned for engagement by said retainer in said second position.

11. A holder for a sample-holding plate defining one or more sample-holding wells, said holder being mounted in a movable carrier and comprising a back wall and a side wall and defining a space between said back wall and said side wall into which a sample-holding plate can be placed, said holder further comprising a retainer mounted to a holder frame for movement relative to said space between a first position for pressing a sample-holding plate placed in said space against both said back wall and said side wall and a second position retracted from pressing the sample-holding plate, said retainer comprising an arm defining a pressing surface disposed for pressing engagement with the sample-holding plate, and said retainer having a basic shape of an obtuse V and being pivoted by its apex to a vertical pin in the moveable carrier, and said holder further comprising a spring linked to said retainer with a first end against a frame of the moveable carrier and an opposite second end against said retainer.

18. A holder for a sample-holding plate defining one or more sample-holding wells, said holder comprising a back wall and a side wall and defining a space between said back wall and said side wall into which a sample-holding plate can be placed,

characterized in that

said holder further comprises a retainer mounted to a holder frame for movement relative to said space between a first position for pressing a sample-holding plate placed in said space against both said back wall and said side wall and a second position retracted from pressing the sample-holding plate, said retainer comprising an arm defining a pressing surface disposed for pressing engagement with the sample-holding plate, said holder being mounted in a moveable carrier and having a front edge opening into said space in a specific loading position of said moveable carrier at which the sample-holding plate is placed into said space or removed therefrom by substantially horizontal motion, and

said holder further comprising pins detachably mounted at said opening for resisting placing or removal of the sample-holding plate in said space when the moveable carrier is removed out of its specific loading position.

19. A holder for a sample-holding plate defining one or more sample-holding wells, said holder comprising a back wall and a side wall and defining a space between said back wall and said side wall into which a sample-holding plate can be placed,

characterized in that

said holder further comprises a retainer mounted to a holder frame for movement relative to said space between a first position for pressing a sample-holding plate placed in said space against both said back wall and said side wall and a second position retracted from pressing the sample-holding plate, said retainer comprising a lever arm mounted for pivoting movement about a pin extending generally vertically from said holder frame.

20. A holder for a sample-holding plate defining one or more sample-holding wells, said holder comprising a back wall and a side wall and defining a space between said back wall and said side wall into which a sample-holding plate can be placed,

characterized in that

said holder further comprises a retainer mounted to a holder frame for movement relative to said space between a first position for pressing a sample-holding plate placed in said space against both said back wall and said side wall and a second position retracted from pressing the sample-holding plate, and sample-holding plate positioning and retaining means consisting of an arm mounted for movement relative to said space between a first position for pressing a sample-holding plate placed in said space against both said back wall and said side wall and a second position retracted from pressing the sample-holding plate, and a spring urging said arm toward said first position.