Materials and methods utilizing a temporary visual indicator

• US 5,997,891 A
• Filed: 08/18/1998
• Issued: 12/07/1999
• Est. Priority Date: 05/13/1993
• Status: Expired due to Fees

• Current Assignee: Christopher D. Batich, Richard J. Melker, Ronnie S. Fuerst
• Original Assignee: IPA
• Inventors: Batich, Christopher D., Melker, Richard, Fuerst, Ronnie S.
• Primary Examiner(s): Dodson, Shelley A.
• Application Number:
  US09/135,768
• Time in Patent Office: 476 Days
• Field of Search: 424/59, 424/78.02, 424/400, 424/401, 273/363, 273/418, 514/470, 549/308, 503/201
• US Class Current: 424/401
• CPC Class Codes: A61K 2800/45 Colour indicators, e.g. pH- or Redox indicators
• CPC Class Codes: A61K 6/20 Protective coatings for natural or artificial teeth, e.g. sealings, dye coatings or varnish
• CPC Class Codes: A61K 6/65 Dyes
• CPC Class Codes: A61K 8/046 Aerosols; Foams
• CPC Class Codes: A61K 8/4973 with oxygen as the only hetero atom
• CPC Class Codes: A61Q 17/04 Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
• CPC Class Codes: C09D 7/00 Features of coating compositions, not provided for in group C09D5/00 driers C09F9/00; Processes for incorporating ingredients in coating compositions
• CPC Class Codes: C11D 3/40 Dyes ; Pigments
• CPC Class Codes: G01N 31/221 for investigating pH value
• CPC Class Codes: Y10T 428/13 Hollow or container type article [e.g., tube, vase, etc.]
• CPC Class Codes: Y10T 428/1352 Polymer or resin containing [i.e., natural or synthetic]
• CPC Class Codes: Y10T 428/1397 Single layer [continuous layer]
• CPC Class Codes: Y10T 428/249995 Constituent is in liquid form
• CPC Class Codes: Y10T 428/249997 Encapsulated liquid

Abstract

This invention relates to novel compositions containing temporary visual indicators and methods for using these compositions. Specifically, this invention relates to a sunscreen composition containing an indicator that is visible when the substance is applied to the skin, but becomes invisible shortly after application. The continued presence of the indicator allows the indicator to be reactivated temporarily to the visible form so that a user can verify the presence of the sunscreen. The visible indicator ensures that the sunscreen is applied evenly and completely to the area to be protected, but becomes invisible so as not to interfere with the action of the sunscreen or discolor the skin.

Claims

1. A composition for human or animal use comprising:

(a) a spray or lotion for application to a body surface of the animal or human;

(b) an indicator for which a change of pH from a first pH to a second pH causes either (i) a change from one color to another color, or (ii) a change from colorless to a color, or (iii) a change from a color to colorless; and

(c) a pH-modifying substance in an amount sufficient to establish the pH of the composition at said first pH and which evaporates or degrades thereby causing the pH to change to said second pH.

2. The composition, according to claim 1, wherein said spray or lotion is a suntan product.

3. The composition, according to claim 1, wherein said spray or lotion is antibacterial or an antiseptic.

4. The composition, according to claim 1, wherein said spray or lotion is a topical dermatological.

5. The composition, according to claim 1, wherein said spray or lotion is an ophthalmological solution.

6. The composition, according to claim 1, wherein said indicator is 3,3-bis [4-hydroxyphenyl]-1-[3H]-isobenzofuranone.

7. The composition, according to claim 1, wherein said pH modifying substance is a volatile base.

8. A composition comprising:

(a) a first component selected from a group consisting of paints, lacquers, sealants, protectants, polishes, varnishes, herbicides, pesticides and fertilizers;

(b) an indicator for which a change of pH from a first pH to a second pH causes either (i) a change from one color to another color, or (ii) a change from colorless to a color, or (iii) a change from a color to colorless; and

(c) a pH-modifying substance in an amount sufficient to establish the pH of the composition at said first pH and which evaporates or degrades thereby causing the pH to change to said second pH.

9. The composition, according to claim 8, wherein said indicator is 3,3-bis[4 hydroxyphenyl]-1-[3H]-isobenzofuranone.

10. The composition, according to claim 8, wherein said pH-modifying substance is a volatile base.

11. A cosmetic composition which is applied to the skin to modify the effects of solar radiation, wherein said composition comprises:

(a) a first ingredient which, when applied to the skin and exposed to air or sunlight, changes its chemical form, thereby causing a change in pH of the composition; and

(b) a second ingredient which gives a visual indication of a pH change of the composition.

12. The composition, according to claim 11, wherein said second ingredient is 3,3-bis[4-hydroxphenyl]-1-[3H]-isobenzofuranone.

13. The composition, according to claim 11, wherein said first ingredient is a monoamine.

14. The composition, according to claim 11, wherein said first ingredient is a diamine.

15. The composition, according to claim 11, wherein said first ingredient is a cyclic amine.

16. The composition, according to claim 13, wherein said monoamine is ammonia.

17. The composition, according to claim 14, wherein said diamine is 1,3-diaminopropane.

18. A sunscreen composition, comprising:

a component capable of protecting human skin from exposure to harmful ultraviolet radiation; and

a temporary visual indicator capable of changing color from a color visible to a human eye, upon application to human skin to ensure that the sunscreen is applied evenly and completely to areas to be protected, to a color indicator that is not substantially visible to the eye upon application and distribution to the skin.

19. A sunscreen composition for application to human skin, comprising:

a compound for protecting the skin from solar radiation; and

a temporary visual indicator that provides a non-white appearance when applied to the skin, the composition disappearing through evaporation in less than about two minutes.

20. A sunscreen composition according to claim 19, wherein the temporary visual indicator provides a pink appearance.

21. A sunscreen composition according to claim 19, further comprising a base selected for its rate of evaporation on the skin.

22. A sunscreen composition according to claim 19, wherein the temporary visual indicator comprises a water soluble dye.

23. A sunscreen composition for application to human skin, comprising:

a compound for protecting the skin from solar radiation;

a volatile base for adjusting the pH of the composition, the base evaporating once applied to the skin; and

a temporary visual indicator that provides a non-white appearance when applied to the skin, the composition disappearing during evaporation of the base.

24. A composition according to claim 23, where in the evaporation occurs between about fifteen seconds and two minutes.

25. A sunscreen composition for application to human skin, the composition having a pH suitable for application to the skin, comprising:

a compound for protecting the skin from solar radiation; and

a temporary visual indicator that provides a non-white color when applied to the skin, the pH changing after application to the skin whereby the visual indicator changes to a second color after a period of time between about fifteen seconds and two minutes.

26. A composition according to claim 25, further comprising a volatile base for adjusting the composition to the pH.

27. A sunscreen composition for application to human skin, the composition having a pH suitable for application to the skin, comprising:

a compound for protecting the skin from solar radiation;

a volatile base for adjusting the composition to the pH, the base evaporating once applied to the skin; and

a temporary visual indicator that provides a non-white color when applied to the skin, the pH changing after application to the skin through evaporation of the base whereby the visual indicator changes to a second color after a period of time between about fifteen seconds and two minutes.

28. A sunscreen composition for application to human skin, the composition having a pH suitable for application to the skin, comprising:

a compound for protecting the skin from solar radiation;

a volatile base for adjusting the composition to the pH, the base evaporating once applied to the skin; and

a temporary visual indicator that provides a non-white color when applied to the skin, the pH changing after application to the skin through evaporation of the base whereby the composition disappears after a period of time between about fifteen seconds and two minutes.

29. A composition for application to human skin, comprising a sunscreen compound and at least one water-soluble dye that imparts a non-white color to the sunscreen composition, the composition evaporating after application on the skin and becoming invisible.

30. A composition according to claim 29, further comprising a volatile base for adjusting the composition to a pH suitable for human skin, prior to application thereon, and for evaporating at a desired rate after application such that the composition changes color.

31. A composition according to claim 29, further comprising a volatile base for adjusting the composition to a pH suitable for human skin, prior to application thereon, and for evaporating at a desired rate after application such that the composition becomes invisible.

32. A composition according to claim 29, wherein the dye comprises a temporary visual indicator.

33. A composition according to claim 29, wherein the dye comprises thymol blue.

34. A composition according to claim 29, wherein the dye comprises bromthymol blue.

35. A composition according to claim 29, wherein the dye comprises phenolphthalein.

36. A composition according to claim 29, further comprising a base which evaporates after application, thereby modifying the pH of the composition.

37. A composition according to claim 29, wherein the dye is responsive to changes in pH to change color.

38. A method of applying sunscreen composition to ensure uniform application and coverage to skin, comprising the steps of:

providing a water soluble dye that is visible to human eye; and

applying the composition and the dye to the skin to ensure that the sunscreen composition is applied evenly and uniformly, the dye becoming colorless through evaporation after application to the skin.

39. A composition for application to human skin, comprising a sunscreen compound and at least one water-soluble dye that imparts a non-white color to the sunscreen composition, the composition becoming invisible after application on the skin.

40. A composition according to claim 39, further comprising a volatile base for adjusting the composition to a pH suitable for human skin, prior to application thereon, and for evaporating at a desired rate after application such that the composition changes color.

41. A composition according to claim 39, further comprising a volatile base for adjusting the composition to a pH suitable for human skin, prior to application thereon, and for evaporating at a desired rate after application such that the composition becomes invisible.

42. A composition according to claim 39, wherein the dye comprises a temporary visual indicator.

43. A composition according to claim 39, wherein the dye comprises thymol blue.

44. A composition according to claim 39, wherein the dye comprises bromthymol blue.

45. A composition according to claim 39, wherein the dye comprises phenolphthalein.

46. A composition according to claim 39, further comprising a base which evaporates after application, thereby modifying the pH of the composition.

47. A composition for application to human skin, comprising a sunscreen compound, water and at least one water-soluble dye that imparts a non-white color to the sunscreen composition, the composition becoming invisible after application on the skin and exposure to carbon dioxide.

48. A composition for application to human skin, comprising a sunscreen compound, water, a base for adjusting the composition to a pH suitable for human skin, prior to application thereon, and at least one water-soluble dye that imparts a non-white color to the sunscreen composition, wherein carbon dioxide adjusts the pH of the composition such that the composition changes color after application to the skin.

49. A composition according to claim 48, wherein the dye comprises a temporary visual indicator.

50. A composition according to claim 48, wherein the dye comprises thymol blue.

51. A composition according to claim 48, wherein the dye comprises bromthymol blue.

52. A composition according to claim 48, wherein the dye comprises phenolphthalein.

53. A composition according to claim 48, wherein the base evaporates after application, thereby modifying the pH of the composition.

54. A sunscreen composition comprising:

one or more sunscreen ingredients; and

at least one water soluble dye which imparts to the composition a color, other than white, and which is visible after the composition is spread on human skin but which substantially disappears when rubbed into the skin.

55. A sunscreen composition comprising:

one or more sunscreen ingredients; and

at least one water soluble dye which imparts to the composition a color, other than white, and which is visible after the composition is spread on human skin but which loses its color when rubbed into the skin.

56. A sunscreen composition comprising:

one or more sunscreen ingredients; and

at least one water soluble dye which imparts to the composition a color, other than white, and which is visible when initially applied on human skin but which loses its color when distributed over the skin.

57. A sunscreen composition comprising:

one or more sunscreen ingredients; and

at least one water soluble which imparts to the composition a color, other than white, and which is visible when initially applied on human skin but which substantially disappears when distributed over the skin.