Detection of cancerous lesions by their effect on the spatial homogeneity of skin temperature

• US 5,999,843 A
• Filed: 04/20/1998
• Issued: 12/07/1999
• Est. Priority Date: 01/03/1995
• Status: Expired due to Fees

• Current Assignee: Omnicorder Technologies, Inc. (Advanced BioPhotonics, Inc.)
• Original Assignee: Omnicorder Technologies, Inc. (Advanced BioPhotonics, Inc.)
• Inventors: Anbar, Michael
• Primary Examiner(s): Casler, Brian L.
• Application Number:
  US09/063,129
• Time in Patent Office: 596 Days
• Field of Search: 600/473, 600/474, 600/475, 600/549, 600/555, 600/504
• US Class Current: 600/474
• CPC Class Codes: A61B 2010/008 Interstitial fluid
• CPC Class Codes: A61B 5/015 By temperature mapping of body part
• CPC Class Codes: A61B 5/7257 using Fourier transforms
• CPC Class Codes: G01N 33/574 for cancer
• CPC Class Codes: G01N 33/57415 of breast
• CPC Class Codes: G06T 2207/10048 Infrared image
• CPC Class Codes: G06T 2207/20056 Discrete and fast Fourier transform, [DFT, FFT]
• CPC Class Codes: G06T 2207/30068 Mammography; Breast
• CPC Class Codes: G06T 2207/30096 Tumor; Lesion
• CPC Class Codes: G06T 7/0012 Biomedical image inspection
• CPC Class Codes: G06T 7/42 using transform domain methods

Abstract

The present invention comprises methods for cancer detection involving the measurement of temporal periodic changes in blood perfusion, associated with immune response, occurring in neoplastic lesions and their surrounding tissues. Particularly, the method for cancer detection involves the detection of non-neuronal thermoregulation of blood perfusion, periodic changes in the spatial homogeneity of skin temperature, aberrant oscillations of spatial homogeneity of skin temperature and aberrant thermoregulatory frequencies associated with periodic changes in the spatial homogeneity of skin temperature.

Claims

1. A method for detecting breast canter tissue in a human, comprising the steps of:

a) providing a detection device for detecting periodic changes in spatial homogeneity of temperature in areas of a human breast; and

b) measuring, with the detection device, periodic changes in spatial homogeneity of temperature in areas of the human breast to thereby determine a likelihood of cancerous tissue in the human.

2. The method of claim 1 wherein the periodic changes in spatial homogeneity of temperature in areas of the human breast are measured using DAT.

3. The method of claim 1 wherein the detection device includes an infrared imaging and sensing system.

4. A method for detecting cancerous tissue in a human, comprising the steps of:

a) providing a device for measuring infrared flux emitted from a plurality of areas human skin;

b) measuring infrared flux emitted from the plurality of areas of the human skin;

c) detecting periodic oscillations in the infrared flux emitted from the plurality of areas of human skin; and

d) detecting changes in the periodic oscillations in the infrared flux emitted from the plurality of areas of the human skin to thereby determine a likelihood of cancerous tissue in the human.

5. The method of claim 4 wherein the changes in periodic oscillation in the infrared flux emitted from the plurality of areas of the skin are detected using DAT.

6. The method of claim 4 wherein the measuring device includes an infrared imaging and sensing system.

7. A method for detecting cancer in a human body, comprising the steps of:

a) providing a detection device for detecting periodic changes in the spatial homogeneity of temperature in areas of human skin; and

b) measuring with the detection device periodic changes in the spatial homogeneity of temperature in areas of the human skin to thereby determine a likelihood of cancer in the human body.

8. The method of claim 7 wherein the periodic changes in the spatial homogeneity of temperature in areas of the human skin are measured using DAT.

9. The method of claim 7 wherein the detecting device includes an infrared imaging and sensing system.

10. The method of claim 7 comprising the additional steps of:

a) providing a device for cooling the human skin; and

b) cooling, with the cooling device, the human skin to accentuate the variances between cancerous and non-cancerous areas of the human skin.