Smooth ventricular assist device conduit

• US 6,001,056 A
• Filed: 11/13/1998
• Issued: 12/14/1999
• Est. Priority Date: 11/13/1998
• Status: Expired due to Term

• Current Assignee: World Heart Corporation (Medtronic Plc)
• Original Assignee: Baxter International Inc.
• Inventors: Shannon, Donald T., Chen, Herbert, Jassawalla, Jal S.
• Primary Examiner(s): Getzow, Scott M.
• Application Number:
  US09/191,506
• Time in Patent Office: 396 Days
• Field of Search: 600/16, 600/17, 600/18, 623/3
• US Class Current: 600/16
• CPC Class Codes: A61F 2/2412 with soft flexible valve members, e.g. tissue valves shaped like natural valves check valves with flexible valve members in general F16K15/14
• CPC Class Codes: A61M 60/122 Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body
• CPC Class Codes: A61M 60/148 in line with a blood vessel using resection or like techniques, e.g. permanent endovascular heart assist devices
• CPC Class Codes: A61M 60/857 Implantable blood tubes
• CPC Class Codes: A61M 60/859 Connections therefor
• CPC Class Codes: A61M 60/88 Percutaneous cables
• CPC Class Codes: A61M 60/896 having flexible or resilient parts, e.g. flap valves

Abstract

A smooth-walled non-crimped inflow conduit for an implantable ventricular assist system. The conduit has an internally smooth lumen surface for enhanced washing of the conduit under irregular blood flow conditions. The conduit includes a tubular graft body that may be formed of a knitted fabric sealed with bovine collagen or gelatin, or formed of closed structured PTFE. The conduit may include external ribbing or support to prevent inward collapse under negative pressure conditions and also protect against damage from inadvertent physical contact in the operating room. The external support may be bonded to the exterior or formed integrally with the tubular graft body. An outer reinforcement cage may be provided to help prevent gross distortion or damage to the tubular graft body. The ends of the tubular graft body are left unsupported and wrapped around opposed lips of conduit coupling structure to minimize blood contacting surfaces at junctions with other conduits or with the heart. The conduit may be provided in an implantable left ventricular assist system also including a pumping device, valved conduits, and a power supply.

Claims

1. An inflow conduit for an implantable ventricular assist device, comprising:

a flexible tubular graft body having an upstream end and a downstream end, the body having a substantially smooth inner surface for enhanced flow-through of blood with a minimum of surface-induced turbulence;

a ventricular attachment structure to which the upstream end of the body connects; and

a coupling fitting on the downstream end of the body.

2. The inflow conduit of claim 1, wherein the tubular graft body is a knitted fabric.

3. The inflow conduit of claim 1, wherein the tubular graft body is a polyethylene terephthalate fabric.

4. The inflow conduit of claim 1, wherein the tubular graft body is a fabric having a biocompatible sealant impregnated therein.

5. The inflow conduit of claim 4, wherein the sealant is bovine gelatin.

6. The inflow conduit of claim 4, wherein the sealant is bovine collagen.

7. The inflow conduit of claim 1, further including an external support secured to an external surface of the tubular graft body.

8. The inflow conduit of claim 7, wherein the external support comprises a helically wound coil.

9. The inflow conduit of claim 7, wherein the external support comprises a helically wound polypropylene coil thermally bonded to the external surface of the tubular graft body.

10. The inflow conduit of claim 1, wherein the tubular graft body is made of PTFE.

12. The inflow conduit of claim 10, further including a plurality of reinforcement members secured to an external surface of the tubular graft body.

13. The inflow conduit of claim 12, wherein the plurality of reinforcement members are fonned by a helically wound coil.

14. The inflow conduit of claim 13, wherein the helically wound coil is wound tighter at the opposed ends of the tubular graft body than in the middle portion.

15. The inflow conduit of claim 1, wherein the ventricular attachment structure on the upstream end of the graft includes a tubular cannula portion having a distal rim for extending into the ventricle, and an external apical ring spaced from the distal rim for sewing to the external ventricle wall, the upstream end of the graft extending through the cannula portion and being wrapped around the distal rim to lie against the exterior of the cannula portion and attach to the apical ring.

11. The inflow conduit of claim 11, wherein the PTFE is closed structured to resist tissue ingrowth from the exterior of the tubular graft body.

16. An inflow conduit for an implantable ventricular assist device, comprising:

a flexible tubular graft body having a smooth inner surface and an external kink-resistive supporting structure, the graft having opposed ends;

a ventricular attachment structure on one end of the tubular graft body; and

a coupling fitting on the other end of the tubular graft body.

17. The inflow conduit of claim 16, wherein the tubular graft body is a fabric having a biocompatible sealant impregnated therein.

18. The inflow conduit of claim 16, wherein the tubular graft body is made of closed structured PTFE to resist tissue ingrowth from the exterior of the tubular graft body.

19. The inflow conduit of claim 16, wherein the supporting structure comprises a helically wound coil.

20. The inflow conduit of claim 19, wherein the helically wound coil is wound tighter at the opposed ends of the tubular graft body than in the middle portion.

21. The inflow conduit of claim 19, wherein the helically wound coil is polypropylene thermally bonded to the external surface of the tubular graft body.

22. The inflow conduit of claim 19, wherein the helically wound coil is PTFE bonded to the external surface of the tubular graft body.

23. The inflow conduit of claim 19, wherein the helically wound coil is formed integrally with the tubular graft body.

24. An inflow conduit for an implantable ventricular assist device, comprising:

a flexible tubular graft body having an upstream end and a downstream and a smooth, non-convoluted interior lumen; and

a ventricular attachment structure on the upstream end of the graft including a tubular cannula portion having a distal rim for extending into the ventricle, and an external apical ring spaced from the distal rim for sewing to the external ventricle wall, the upstream end of the graft extending through the cannula portion and being wrapped around the distal rim to lie against the exterior of the cannula portion and attach to the apical ring.

25. The inflow conduit of claim 24, wherein the tubular graft body is a knitted fabric.

26. The inflow conduit of claim 24, wherein the tubular graft body is a polyethylene terephthalate fabric.

27. The inflow conduit of claim 24, wherein the tubular graft body is a fabric having a biocompatible sealant impregnated therein.

28. The inflow conduit of claim 27, wherein the sealant is bovine gelatin.

29. The inflow conduit of claim 27, wherein the sealant is bovine collagen.

30. The inflow conduit of claim 24, further including an external support secured to an external surface of the tubular graft body.

31. The inflow conduit of claim 24, wherein the tubular graft body is made of PTFE.

32. The inflow conduit of claim 31, wherein the PTFE is closed structured to resist tissue ingrowth from the exterior of the tubular graft body.

33. The inflow conduit of claim 32, further including a plurality of PTFE reinforcement members integrally formed on the external surface of the tubular graft body.

34. An implantable ventricular assist device, comprising:

an inflow conduit including;

a flexible tubular graft body having an upstream end and a downstream end, the body having a substantially smooth inner surface for enhanced flow-through of blood with a minimum of surface-induced turbulence;

a ventricular attachment structure to which the upstream end of the body connects; and

a coupling fitting on the downstream end of the body;

an implantable pumping portion in flow communication with the inflow conduit; and

an outflow conduit in flow communication with the pumping portion.

35. The device of claim 34, wherein the tubular graft body is a knitted fabric having a biocompatible sealant impregnated therein.

36. The device of claim 34, wherein the tubular graft body is made of closed structured PTFE to resist tissue ingrowth from the exterior of the tubular graft body.

37. The device of claim 34, wherein the outflow conduit includes a tubular graft body having a convoluted construction.