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Contrasting agents for ultrasonic imaging and methods for preparing the same

  • US 6,001,335 A
  • Filed: 06/18/1996
  • Issued: 12/14/1999
  • Est. Priority Date: 12/22/1989
  • Status: Expired due to Term
First Claim
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1. A method for synthesizing a lipid vesicle for use in ultrasound imaging, the lipid vesicle having encapsulated therein a gas, wherein the method comprises subjecting a solvent-free composition which comprises a gaseous precursor and a lipid in an aqueous medium to a first pressure and thereafter subjecting said composition to a second pressure, wherein said second pressure is a decreased pressure.

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