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Process for producing solid drug forms having at least two phases

  • US 6,001,391 A
  • Filed: 03/10/1998
  • Issued: 12/14/1999
  • Est. Priority Date: 03/12/1997
  • Status: Expired due to Term
First Claim
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1. A process for producing solid combination drug forms which have at least a first phase and a second phase, wherein at least the first phase contains a pharmacologically acceptable polymeric binder and at least one of the first and the second phase contains a pharmaceutically active ingredient, comprising(i) providing a plastic melt of a polymeric binder (binder A) with or without at least one active ingredient, which forms the first phase,(ii) molding the plastic melt to the drug form, and(iii) incorporating in the plastic melt during the molding step at least one solid product which may contain at least one active ingredient which solid product forms the second phase.

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