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Methods and apparatus for in situ concentration and/or dilution of materials in microfluidic systems

  • US 6,004,515 A
  • Filed: 10/27/1998
  • Issued: 12/21/1999
  • Est. Priority Date: 06/09/1997
  • Status: Expired due to Term
First Claim
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1. A method of diluting a first fluid in a microfluidic device, comprising:

  • introducing a first fluid into a first channel in a microfluidic device;

    adding a second fluid to the first fluid in the first channel, the first and second fluids mixing in the first channel;

    removing a portion of the first and second fluids mixed in the first channel;

    adding a third fluid to the first channel to mix with the first and second fluids mixed in the first channel, thereby diluting the first fluid with the second and third fluids in the first channel.

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