Nucleic acids encoding immunoglobulin domains
First Claim
Patent Images
1. An isolated nucleic acid molecule encoding the immunoglobulin complementarity determining region shown in SEQ ID NOs:
- 9 or 10.
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0 Petitions
Accused Products
Abstract
Monoclonal antibodies directed against coagulation factors and their use in inhibiting thrombosis are disclosed.
43 Citations
7 Claims
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1. An isolated nucleic acid molecule encoding the immunoglobulin complementarity determining region shown in SEQ ID NOs:
- 9 or 10.
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2. An isolated nucleic acid molecule encoding the immunoglobulin complementarity determining region shown in SEQ ID NOs:
- 12 or 14.
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3. An isolated nucleic acid molecule encoding SEQ ID NO:
- 52 or functional fragments thereof.
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4. An isolated nucleic acid molecule encoding SEQ ID NO:
- 74 or functional fragments thereof.
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5. An isolated nucleic acid molecule encoding SEQ ID NOs:
- 31, 44, 52, 57, 62, 74, 78, 89 or 99 or functional fragments thereof.
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6. An isolated nucleic acid molecule encoding the immunoglobulin complementarity determining regions having the amino acid sequences shown in SEQ ID NOs:
- 8, 9 and 10.
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7. An isolated nucleic acid molecule encoding the immunoglobulin complementarity determining regions having the amino acid sequences shown in SEQ ID NOs:
- 12, 13 and 14.
Specification