Non-invasive optical measurement of blood hematocrit
First Claim
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1. A method for determining blood hematocrit, the method comprising:
- irradiating blood with optical radiation to produce an optical spectrum, the optical radiation comprising a selected range of optical wavelengths, the wavelengths in the selected range being affected by the presence of a plurality of red blood cell constituents including hemoglobins and cellular bodies; and
processing the optical spectrum with a mathematical model to determine the blood hematocrit, the model being constructed by relating optical properties of the plurality of red blood cell constituents to known blood hematocrit.
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Abstract
The invention provides an optical method and apparatus for non-invasively determining blood hematocrit. The method includes the step of first irradiating blood with optical radiation. Radiation reflected or transmitted from the blood is then collected to determine an optical spectrum. Hematocrit is then determined by comparing this spectrum to a mathematical model relating optical properties to blood Hematocrit.
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Citations
16 Claims
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1. A method for determining blood hematocrit, the method comprising:
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irradiating blood with optical radiation to produce an optical spectrum, the optical radiation comprising a selected range of optical wavelengths, the wavelengths in the selected range being affected by the presence of a plurality of red blood cell constituents including hemoglobins and cellular bodies; and processing the optical spectrum with a mathematical model to determine the blood hematocrit, the model being constructed by relating optical properties of the plurality of red blood cell constituents to known blood hematocrit. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15)
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16. A method for determining blood hematocrit, the method comprising:
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irradiating blood with optical radiation to produce an optical spectrum, the optical radiation comprising a selected range of optical wavelengths limited to a range of about 500 nm to 1100 nm, the wavelengths in the selected range being affected by the presence of a plurality of red blood cell constituents; and processing the optical spectrum with a mathematical model to determine the blood hematocrit, the model being constructed by relating optical properties of the plurality of red blood cell constituents to known blood hematocrit.
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Specification