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Antisense oligonucleotides for mitogen-activated protein kinases as therapy for cancer

  • US 6,007,991 A
  • Filed: 08/12/1997
  • Issued: 12/28/1999
  • Est. Priority Date: 03/28/1997
  • Status: Expired due to Fees
First Claim
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1. A method of inhibiting growth of malignant breast tumors in a mammal, which comprises injecting directly into the tumor an effective amount of an oligonucleotide having 10-100 nucleotides and complementary to the initiation codon of ERK-1 or ERK-2.

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