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Enhanced transdermal transport of fluid using vacuum

  • US 6,009,343 A
  • Filed: 02/23/1996
  • Issued: 12/28/1999
  • Est. Priority Date: 02/23/1996
  • Status: Expired due to Term
First Claim
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1. A process of sampling extracellular fluid from an animal having skin comprising the steps of:

  • (a) applying ultrasound to a region of the skin of the animal,(b) applying reduced pressure at or near the region of the skin where ultrasound has been applied, and(c) collecting extracellular fluid from the animal;

    wherein steps (a) and (b) are performed either sequentially or simultaneously.

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