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Apparatus and method for performing microfluidic manipulations for chemical analysis and synthesis

  • US 6,010,608 A
  • Filed: 09/16/1998
  • Issued: 01/04/2000
  • Est. Priority Date: 08/01/1994
  • Status: Expired due to Term
First Claim
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1. A method for separating component species in a sample, comprising:

  • providing a microfluidic device that includes a body having at least first, second, third and fourth channels disposed therein, the first, second, third and fourth channels communicating at a first intersection, the first channel connecting at least a first sample source to the first intersection;

    transporting a sample material from the first sample source, through the first intersection and into the second channel by applying a first voltage difference between the first sample material source and the second channel to move sample material from the first channel, through the intersection and into the second channel, and simultaneously applying a second voltage differences between the third channel and the first intersection and a third voltage difference between the fourth channel and the first intersection, to direct movement of the sample material through the intersection into the second channel;

    injecting an amount of sample material in the first intersection into the third channel by applying a fourth voltage difference between the first intersection and the third channel, the component species of the sample material separating as the sample material is transported through the third channel.

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