Medical article with adhered antimicrobial metal ions and related methods
First Claim
1. A biocompatible article comprising a biocompatible material forming at least a portion of said biocompatible article, a macromolecular, exogenous storage structure bound to said biological material and antimicrobial metal ions reversibly bound to said exogenous storage structure.
1 Assignment
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Accused Products
Abstract
Biocompatible articles for placement in a patient are described having releasably adhered antimicrobial metal ions. Furthermore, biocompatible articles made from biocompatible material for subcutaneous, percutaneous and cutaneous use are described where the biocompatible material has an attached exogenous storage structure with reversibly bound antimicrobial metal ions. The exogenous storage structures can include proteins such as ferritin, globulins, albumin, glutathione, transferrin, hemoglobin, metallothiens, myoglobin, ceruloplasmin and hemocyanin. Associated methods for imparting antimicrobial properties to biocompatible articles are described.
67 Citations
8 Claims
- 1. A biocompatible article comprising a biocompatible material forming at least a portion of said biocompatible article, a macromolecular, exogenous storage structure bound to said biological material and antimicrobial metal ions reversibly bound to said exogenous storage structure.
Specification