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Water-insoluble derivatives of hyaluronic acid and their methods of preparation and use

  • US 6,013,679 A
  • Filed: 12/05/1995
  • Issued: 01/11/2000
  • Est. Priority Date: 08/01/1989
  • Status: Expired due to Fees
First Claim
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1. A method for preparing a water-insoluble biocompatible gel, comprising reacting hyaluronic acid, or a salt thereof, with a carbodiimide to form a water insoluble gel in the absence of a nucleophile and a polyanionic polysaccharide other than the hyaluronic acid of the reaction.

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