System and method for stabilizing and removing tissue

• US 6,015,390 A
• Filed: 06/12/1998
• Issued: 01/18/2000
• Est. Priority Date: 06/12/1998
• Status: Expired due to Term

• Current Assignee: Varian Medical Systems Incorporated (Siemens AG)
• Original Assignee: D. KRAG, LLC
• Inventors: Krag, David N.
• Primary Examiner(s): Hindenburg, Max
• Assistant Examiner(s): SZMAL, BRIAN SCOTT
• Application Number:
  US09/096,807
• Time in Patent Office: 585 Days
• Field of Search: 128/DIG. 27, 128/734, 128/736, 600/549, 607/102, 343/6.5 SS
• US Class Current: 600/549
• CPC Class Codes: A61B 18/02 by cooling, e.g. cryogenic techniques devices for cooling specific reflex points of the body within cell-life limits A61H39/06
• CPC Class Codes: A61B 2017/00084 Temperature
• CPC Class Codes: A61B 2090/374 NMR or MRI
• CPC Class Codes: A61B 2090/3908 Soft tissue, e.g. breast tissue
• CPC Class Codes: A61B 34/10 Computer-aided planning, simulation or modelling of surgical operations
• CPC Class Codes: A61B 90/17 for soft tissue, e.g. breast-holding devices
• CPC Class Codes: Y10S 128/27 Cryogenic

Abstract

A system (8) and method for stabilizing a tissue mass, using temperature sensors (10), a scanner (80), and a cryoprobe (220). The sensors provide temperature information with respect to a tissue portion adjacent thereto. The sensors include an identification (ID) code and an ID decoder. The ID decoder compares the sensor ID code to an ID code contained in an interrogation signal provided by the scanner. If the codes match, the sensor transmits the temperature information to the scanner, which processes and displays the temperature information in a humanly recognizable form. The method includes the step of inserting a cryoprobe into a tissue volume to be stabilized so that a portion of the cryoprobe projects therefrom. Then, the tissue volume is frozen while monitoring the size or temperature of the tissue volume. Freezing is terminated when the tissue volume is frozen (or reaches a first temperature level), and then removed while grasping the cryoprobe so as to stabilize the tissue volume.

Claims

1. A system for use in stabilizing and removing a piece of tissue, the system comprising:

a. a plurality of sensors, each sensor including;

i. a temperature sensor for determining the temperature of the piece of tissue adjacent said each sensor, and for providing a first signal containing information that varies as a function of changes in said temperature;

ii. an antenna for receiving an interrogation signal containing a first identification code;

iii. a memory containing a second identification code;

iv. an ID decoder connected to said antenna and said memory for comparing said first identification code and said second identification code to assess whether said first identification code matches said second identification code; and

b. a scanner for providing said interrogation code.

2. A system according to claim 1, wherein each of said plurality of sensors further includes:

a. a data encoder/multiplexer for multiplexing said first signal and said second identification code to form a multiplexed signal; and

b. a data modulator connected to said data encoder/multiplexer and said antenna for generating a second signal containing said multiplexed signal for transmission by said antenna.

3. A system according to claim 1, wherein said memory is reprogrammable memory capable of being reprogrammed to store different identification codes.

4. A system according to claim 3, wherein said sensor further includes a mode decoder for determining if said interrogation signal includes ID programming code and for placing said sensor in a state in which a new second identification code may be stored in said memory in response to said interrogation signal including said ID programming code.

5. A system according to claim 1, wherein said scanner further includes a display for displaying a humanly recognizable representation of temperature.

6. A system according to claim 5, wherein said display has means for displaying said temperature for each of said plurality of sensors.

7. A system according to claim 1, further wherein:

a. each of said plurality of sensors includes means for generating a second signal containing said information and said second identification code; and

b. said scanner includes;

i. an antenna for receiving said second signal;

ii. a display for displaying temperature data; and

iii. means connected to said antenna and said display for generating said temperature data based on said information in said second signal.

8. A system according to claim 1, further wherein:

a. each of said plurality of sensors includes means for generating a second signal containing said information; and

b. said scanner includes;

i. an antenna for receiving said second signal;

ii. means connected with said antenna for determining based on said information in said second signal whether the temperature of tissue adjacent one or more of said plurality of sensors has fallen below a target temperature, and for generating a third signal following determination that said temperature has fallen below said target temperature; and

iii. an alarm connected to said means for providing a humanly recognizable signal in response to receipt of said third signal.

9. A system according to claim 1, wherein scanner further includes means for:

a. generating a plurality of said first identification codes, each differing from other ones of said plurality of said first identification codes and each associated with a corresponding respective one of said plurality of sensors; and

b. providing said interrogation signal so that it includes said plurality of first identification codes.

10. A system according to claim 1, further wherein:

a. said plurality of sensors includes a first group of sensors and a second group of sensors, each of which includes means for generating a second signal containing said information; and

b. said scanner includes;

i. means for determining based on said information in said second signal (1) whether the temperature of tissue adjacent sensors in said first group of sensors has fallen below a temperature T1 and (2) whether the temperature of tissue adjacent sensors in said second group of sensors has fallen below a temperature T2;

ii. an alarm connected to said means for providing a humanly recognizable signal when said means determines said temperature of tissue adjacent sensors in said first group of sensors has fallen below said temperature T1 or when said means determines said temperature of tissue adjacent sensors in said second group of sensors has fallen below said temperature T2.

11. A system according to claim 1, further including a cryoprobe for freezing the piece of tissue.

12. A system for use in freezing tissue, the system comprising:

a. a plurality of sensors, each sensor for determining the temperature of tissue adjacent thereto and providing a first signal containing (i) information regarding said temperature and (ii) a first identification code that uniquely identifies said each sensor in response to receipt of an interrogation signal having a second identification code that matches said first identification code; and

b. a scanner for receiving said first signal, determining (a) the identity of each of said plurality of sensors based on said identification code and (ii) said temperature of tissue adjacent said each temperature sensor based on said information, and providing a humanly recognizable representation of said temperature of tissue adjacent said each temperature sensor.

13. A system according to claim 12, further including a display for displaying said humanly recognizable representation of said temperature.

14. A system according to claim 12 further including an alarm for indicating if said temperature of one or more of said plurality of sensors has fallen below a target temperature.

15. A system according to claim 12, wherein each of said plurality of sensors further includes:

a. a data encoder/multiplexer for multiplexing said information and said identification code to form a multiplexed signal; and

b. a data modulator connected to said data encoder/multiplexer and said antenna for generating an RF output signal containing said multiplexed signal for transmission by said antenna.

16. A temperature sensor comprising:

a. a temperature measuring unit for measuring the temperature of tissue adjacent thereto and providing a first signal that contains temperature information that varies as a function of changes in said temperature;

b. an antenna for receiving a second signal containing a first identification code;

c. a memory for storing a second identification code; and

d. an identification decoder connected to said antenna and said memory for comparing said first identification code with said second identification code to determine if said first identification code is identical to said second identification code and for generating a third signal when said first identification code is identical to said second identification code.

17. A sensor according to claim 16, wherein said temperature measuring unit includes a thermistor.

18. A sensor according to claim 16, further comprising a data encoder/multiplexer for forming said third signal by multiplexing said second identification code with said information.

19. A sensor according to claim 16, wherein said memory unit is programmable and capable of storing one or more of said second identification codes.

20. A sensor according to claim 19, further comprising a mode decoder for decoding a sensor ID programming code contained in said second signal.