Device for non-invasive determination of a glucose concentration in the blood of a subject
First Claim
1. A device for performing non-invasive determination of a glucose concentration in the blood of a subject, said device comprising:
- a light source for producing near-infrared radiation having successive wavelengths within a range of 1300 nm to 2500 nm;
light projecting means for projecting said near-infrared radiation on a skin of said subject;
light receiving means for receiving a resulting radiation emitted from the inside of said skin; and
spectrum analyzing means for making a spectrum analysis of the resulting radiation and determining said glucose concentration in the blood of said subject according to the spectrum analysis,whereinsaid light receiving means is separated from said light projecting means by a distance in a range of 0.1 mm to 2 mm to permit selective sensing of the resulting radiation emitted from a dermis layer positioned under an epidermis layer of said skin,wherein said spectrum analyzing means determines said glucose concentration in the blood of said subject according to the spectrum analysis and a statistically-obtained correlation between glucose concentration in the dermis layer and glucose concentration in blood,wherein said light projecting means is formed with a plurality of first optical fibers, each of which is connected at a first end to said light source, and provides said near-infrared radiation from an opposite projection end, andwherein said light receiving means is formed with a plurality of second optical fibers each of which is connected at a first end to said spectrum analyzing means, and receives the resulting radiation at an opposite receiving end.
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Accused Products
Abstract
A device for non-invasive determination of a glucose concentration in the blood of a subject which includes a light source for producing near-infrared radiation having successive wavelengths within a range of 1300 nm to 2500 nm, a light projecting unit for projecting the near-infrared radiation on a skin of the subject, a light receiving unit for receiving a resulting radiation emitted from the inside of the skin, and a spectrum analyzing unit for making a spectrum analysis of the resulting radiation, and determining the glucose concentration according to the spectrum analysis. The light receiving unit is separated from the light projecting unit by a distance defined within a range of 0.1 mm to 2 mm to selectively sense the resulting radiation emitted from a dermis layer positioned under an epidermis layer of the skin. The glucose concentration in the blood is determined at the spectrum analyzing unit by using the spectrum analysis and a statistically-obtained correlation between glucose concentration in dermis region and glucose concentration in blood of test subjects.
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Citations
22 Claims
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1. A device for performing non-invasive determination of a glucose concentration in the blood of a subject, said device comprising:
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a light source for producing near-infrared radiation having successive wavelengths within a range of 1300 nm to 2500 nm; light projecting means for projecting said near-infrared radiation on a skin of said subject; light receiving means for receiving a resulting radiation emitted from the inside of said skin; and spectrum analyzing means for making a spectrum analysis of the resulting radiation and determining said glucose concentration in the blood of said subject according to the spectrum analysis, wherein said light receiving means is separated from said light projecting means by a distance in a range of 0.1 mm to 2 mm to permit selective sensing of the resulting radiation emitted from a dermis layer positioned under an epidermis layer of said skin, wherein said spectrum analyzing means determines said glucose concentration in the blood of said subject according to the spectrum analysis and a statistically-obtained correlation between glucose concentration in the dermis layer and glucose concentration in blood, wherein said light projecting means is formed with a plurality of first optical fibers, each of which is connected at a first end to said light source, and provides said near-infrared radiation from an opposite projection end, and wherein said light receiving means is formed with a plurality of second optical fibers each of which is connected at a first end to said spectrum analyzing means, and receives the resulting radiation at an opposite receiving end. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20)
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21. A device for performing non-invasive determination of a glucose concentration in the blood of a subject, said device comprising:
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a light source for producing near-infrared radiation having successive wavelengths within a range of 1300 nm to 2500 nm; a light projecting member which projects said near-infrared radiation on a skin of said subject; a light receiving member which receives a resulting radiation emitted from the inside of said skin; and a spectrum analyzer which makes a spectrum analysis of the resulting radiation and determines said glucose concentration in the blood of said subject according to the spectrum analysis, wherein said light receiving member is separated from said light projecting member by a distance in a range of 0.1 mm to 2 mm to permit selective sensing of the resulting radiation emitted from a dermis layer positioned under an epidermis layer of said skin, and said spectrum analyzer determines said glucose concentration in the blood of said subject according to the spectrum analysis and a statistically-obtained correlation between glucose concentration in the dermis layer and glucose concentration in blood wherein said light projecting member is formed with a plurality of first optical fibers, each of which is connected at a first end to said light source, and provides said near-infrared radiation from an opposite projection end, and wherein said light receiving member is formed with a plurality of second optical fibers each of which is connected at a first end to said spectrum analyzer and receives the resulting radiation at an opposite receiving end. - View Dependent Claims (22)
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Specification