Method of making a blood-compatible antimicrobial surface
First Claim
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1. A method for forming a bacteria-repelling and blood-compatible modified surface on a substrate, comprising the sequential steps of:
- a. activating the surface of a substrate;
b. grafting the resulting activated surface of the substrate with a hydrophilic monomer, andc. subjecting the resulting grafted substrate to an SO2 plasma treatment,whereby bacterial adhesion and blood platelet adhesion to said modified surface after exposure to said plasma treatment is less than prior to said plasma treatment.
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Abstract
A method for making antimicrobial, blood-compatible surfaces is provided, articles having surfaces made by this method, and the use of these articles in fields where controlling the spread of microbes and blood-compatibility are important. Such fields include the medical field, where it is critical to eliminate infection causing microbes and reduce the number of dangerous blood clots in patients.
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Citations
20 Claims
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1. A method for forming a bacteria-repelling and blood-compatible modified surface on a substrate, comprising the sequential steps of:
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a. activating the surface of a substrate; b. grafting the resulting activated surface of the substrate with a hydrophilic monomer, and c. subjecting the resulting grafted substrate to an SO2 plasma treatment, whereby bacterial adhesion and blood platelet adhesion to said modified surface after exposure to said plasma treatment is less than prior to said plasma treatment. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20)
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Specification