Implantable medical device for sensing absolute blood pressure and barometric pressure

• US 6,024,704 A
• Filed: 04/30/1998
• Issued: 02/15/2000
• Est. Priority Date: 04/30/1998
• Status: Expired due to Term

• Current Assignee: Medtronic Incorporated (Medtronic Plc)
• Original Assignee: Medtronic Incorporated (Medtronic Plc)
• Inventors: Miesel, Keith A., Stylos, Lee, Taepke, Robert T. II, Meador, John T., Halperin, Louis E.
• Primary Examiner(s): O'Connor, Cary
• Assistant Examiner(s): CARTER, RYAN CHRISTOPHER
• Application Number:
  US09/070,310
• Time in Patent Office: 656 Days
• Field of Search: 607/2, 607/9, 607/18, 607/27, 600/301, 600/483-486, 600/509, 128/899, 128/903
• US Class Current: 600/486
• CPC Class Codes: A61B 2560/0257 using atmospheric pressure
• CPC Class Codes: A61B 5/0215 by means inserted into the body catheters A61M25/00
• CPC Class Codes: A61B 5/03 Detecting, measuring or recording fluid pressure within the body other than blood pressure, e.g. cerebral pressure; Measuring pressure in body tissues or organs A61B5/205 takes precedence
• CPC Class Codes: A61M 2205/702 automatically during use
• CPC Class Codes: A61M 60/148 in line with a blood vessel using resection or like techniques, e.g. permanent endovascular heart assist devices
• CPC Class Codes: A61M 60/515 Regulation using real-time patient data
• CPC Class Codes: A61M 60/531 using blood pressure data, e.g. from blood pressure sensors
• CPC Class Codes: A61M 60/592 Communication of patient or blood pump data to distant operators for treatment purposes

Abstract

An implantable barometric pressure sensor coupled with an implantable medical device (IMD) provides a barometric pressure related, reference pressure value for use in combination with an absolute pressure value measured by an implantable absolute pressure sensor coupled to the IMD. In one embodiment, the barometric pressure sensor is implanted under the skin and subcutaneous tissue layer at or near the implant site of the IMD. In variations of this embodiment, the barometric pressure is formed as part of a connector module of the IMD or extends from the connector module. In a further embodiment, a percutaneous access device is provided which is adapted to be implanted to extend through the skin and subcutaneous tissue layer of the patient and is coupled with the barometric pressure sensor to provide for an air chamber extending between the atmosphere and the barometric pressure sensor. The barometric pressure sensor is preferably enclosed within an air chamber of the implantable medical device, and a catheter extends between the air chamber of the implantable medical device and the percutaneous access device. Or the barometric pressure sensor is enclosed within an air chamber of the percutaneous access device, and a lead extends between the barometric pressure sensor and the implantable medical device.

Claims

1. A implantable medical device system for measuring barometric pressure within a patient'"'"'s body and for measuring absolute cardiac pressure within the patient'"'"'s heart comprising:

an implantable medical device for powering an absolute pressure sensor and for processing absolute cardiac pressure signal values and for powering a barometric pressure sensor and for processing barometric pressure signal values;

an implantable absolute pressure sensor adapted to be located in a pressure measurement site of the patient'"'"'s heart coupled with said implantable medical device for deriving and providing absolute cardiac pressure signal values to said implantable medical device for processing;

lead means for coupling said implantable absolute pressure sensor with said implantable medical device for providing power to said absolute pressure sensor and for conveying absolute cardiac pressure signal values to said implantable medical device; and

an implantable barometric pressure sensor adapted to be located at a site removed from the patient'"'"'s heart that is not affected by cardiac pressure for deriving and providing barometric pressure signal values to said implantable medical device for processing in conjunction with said absolute cardiac pressure values.

2. The system of claim 1 further comprising means for providing an air passage between said barometric pressure sensor and the atmosphere exterior to the patient'"'"'s body for applying barometric pressure to said barometric pressure sensor.

3. The system of claim 1 wherein said barometric pressure sensor is provided pressure access to bodily fluids through a screen.

4. The system of claim 1 wherein said implantable medical device further comprises an implantable medical device housing adapted to be implanted below the skin and subcutaneous tissue layer of the patient, and said barometric pressure sensor directly attached to said implantable medical device housing.

5. The system of claim 4 further comprising means for providing an air passage between said barometric pressure sensor and the atmosphere exterior to the patient'"'"'s body for applying barometric pressure to said barometric pressure sensor.

6. The system of claim 1 wherein:

said implantable medical device further comprises an implantable medical device housing adapted to be implanted below the skin and subcutaneous tissue layer of the patient; and

said implantable barometric pressure sensor further comprises means extending through said implantable medical device housing for coupling said implantable barometric pressure sensor with said implantable medical device for providing power to said barometric pressure sensor and for conveying barometric pressure signal values to said implantable medical device.

7. The system of claim 1 wherein said implantable medical device further comprises:

a hermetically sealed implantable medical device housing adapted to be implanted below the skin and subcutaneous tissue layer of the patient;

feedthrough means extending through said hermetically sealed implantable medical device housing; and

means for mounting said implantable barometric pressure sensor to said feedthrough means exterior to said hermetically sealed implantable medical device housing for providing power to said barometric pressure sensor and for conveying barometric pressure signal values to said implantable medical device.

8. The system of claim 7 further comprising means for providing an air passage between said barometric pressure sensor and the atmosphere exterior to the patient'"'"'s body for applying barometric pressure to said barometric pressure sensor.

9. The system of claim 1 wherein said implantable medical device further comprises:

a hermetically sealed implantable medical device housing adapted to be implanted below the skin and subcutaneous tissue layer of the patient;

a connector module coupled with said hermetically sealed implantable medical device housing for receiving said lead means;

feedthrough means extending through said hermetically sealed implantable medical device housing and into said connector module; and

a connector block bore for accessing said feedthrough means; and

said implantable barometric pressure sensor further comprises lead means having a lead connector end adapted to be inserted into said connector bore for making connection with said feedthrough means in said connector module exterior to said hermetically sealed implantable medical device housing for providing power to said barometric pressure sensor and for conveying barometric pressure signal values to said implantable medical device.

10. The system of claim 1 wherein:

said implantable medical device further comprises;

hermetically sealed implantable medical device housing adapted to be implanted below the skin and subcutaneous tissue layer of the patient;

a connector module coupled with said hermetically sealed implantable medical device housing for receiving said lead means;

feedthrough means extending through said hermetically sealed implantable medical device housing and into said connector module; and

a connector block bore for accessing said feedthrough means;

a percutaneous access device adapted to be implanted to extend through the patient'"'"' skin having an air vent extending therethrough and an air chamber formed therein; and

said implantable barometric pressure sensor is mounted in said air chamber of said percutaneous access device and further comprises lead means having a lead connector end adapted to be inserted into said connector bore for making connection with said feedthrough means in said connector module exterior to said hermetically sealed implantable medical device housing for providing power to said barometric pressure sensor and for conveying barometric pressure signal values to said implantable medical device.

11. The system of claim 1 further comprising:

a percutaneous access device adapted to be implanted to extend through the patient'"'"' skin having an air vent extending therethrough; and

means for providing an air passage between said barometric pressure sensor and said air vent for applying barometric pressure of air external to the patient'"'"'s body to said barometric pressure sensor.

12. A system for measuring barometric pressure and for measuring absolute pressure within a patient'"'"'s body comprising:

an implantable medical device for powering an absolute pressure sensor and a barometric pressure sensor and for processing barometric pressure signal values and absolute pressure signal values;

an implantable absolute pressure sensor adapted to be located in a pressure measurement site of the patient'"'"'s body coupled with said implantable medical device for deriving and providing absolute pressure signal values to said implantable medical device for processing;

a barometric pressure sensor located in said implantable medical device for deriving and providing barometric pressure signal values to said implantable medical device for processing; and

means for providing an air passage between said barometric pressure sensor and the atmosphere exterior to the patient'"'"'s body for applying barometric pressure to said barometric pressure sensor.

13. A system for measuring barometric pressure and for measuring absolute pressure within a patient'"'"'s body comprising:

an implantable medical device for powering an absolute pressure sensor and a barometric pressure sensor and for processing barometric pressure signal values and absolute pressure signal values;

an implantable absolute pressure sensor adapted to be located in a pressure measurement site of the patient'"'"'s body coupled with said implantable medical device for deriving and providing absolute pressure signal values of fluctuations in a physiologic pressure to said implantable medical device for processing;

a barometric pressure sensor located in said implantable medical device for deriving and providing barometric pressure signal values to said implantable medical device for processing; and

means for providing an air passage between said barometric pressure sensor and the atmosphere exterior to the patient'"'"'s body for applying barometric pressure to said barometric pressure sensor comprising;

a percutaneous access device adapted to be implanted in the patient'"'"'s skin having an air passageway therethrough; and

means coupled between said percutaneous access device and said implantable medical device for applying atmospheric air pressure to said barometric pressure sensor.

14. An implantable medical device method for deriving relative physiologic signal value data for use by and/or storage within an implantable medical device implanted within a patient'"'"'s body comprising the steps of:

implanting an ambient state or condition monitoring device under the skin and subcutaneous tissue layer of the patient'"'"'s body, and with the implanted ambient state or condition monitoring device,

sensing an ambient state or condition outside the body affecting a sensed physiologic state or condition within the body;

deriving a reference signal value from the sensed ambient state or condition; and

conveying the reference signal value to the implantable medical device;

implanting a physiologic state or condition monitoring device in relation with a body organ, and with physiologic state or condition monitoring device, sensing a physiologic state or condition within the body of the patient;

deriving an absolute physiologic signal value from the sensed physiologic state or condition; and

conveying the absolute physiologic signal value to the implantable medical device; and

combining the conveyed absolute physiologic signal value and ambient signal value to derive a relative physiologic signal value therefrom.

15. The method of claim 14, wherein the implantable medical device comprises an implantable monitor or therapy delivery device having implantable device memory and further comprising the step of:

storing a plurality of relative physiologic signal values as relative physiologic signal value data in the implantable medical device memory.

16. The method of claim 14, wherein the implantable medical device comprises an implantable monitor or therapy delivery device having implantable device memory and data conveying means for conveying data stored in the implantable memory to an external memory device and further comprising the steps of:

storing a plurality of relative physiologic signal values as relative physiologic signal value data in the implantable medical device memory; and

activating said data conveying means to convey the relative physiological signal value data stored in the implantable memory to an external medical device.

17. The method of claim 14, wherein the implantable medical device comprises implantable device memory and a therapy delivery system for delivering a therapy to the patient and further comprising the steps of:

storing a predetermined number of relative physiologic signal values as relative physiologic signal value data in the implantable medical device memory; and

employing the relative physiologic signal values to control the delivery of the therapy by the implantable medical device.

18. The method of claim 14, wherein the implantable medical device comprises a therapy delivery system for delivering a therapy to the patient and further comprising the step of:

controlling the delivery of the therapy by the implantable medical device as a function of the relative physiologic signal value.

19. The method of any of the preceding claims 14-18, wherein the physiologic state or condition comprises the blood pressure of the patient, the sensed absolute physiologic signal value is absolute blood pressure value, the ambient state or condition comprises barometric pressure affecting the patient and the absolute pressure value, the relative physiologic signal value is relative blood pressure value;

and the step of combining the derived absolute physiologic signal value and the conveyed ambient signal value comprises subtracting the barometric pressure value from the absolute blood pressure value.

20. An implantable system for deriving relative physiologic signal value data for use by and/or storage within an implantable medical device implanted within a patient'"'"'s body comprising the steps of:

an ambient state or condition monitoring device adapted to be implanted under the skin and subcutaneous tissue layer of the patient'"'"'s body, the implanted ambient state or condition monitoring device further comprising,

means for sensing an ambient state or condition outside the body affecting a sensed physiologic state or condition within the body;

means for deriving a reference signal value from the sensed ambient state or condition; and

means for conveying the reference signal value to the implantable medical device;

a physiologic state or condition monitoring device adapted to be implanted in relation with a body organ, the physiologic state or condition monitoring device further comprising,

means for sensing a physiologic state or condition within the body of the patient;

means for deriving an absolute physiologic signal value from the sensed physiologic state or condition; and

means for conveying the absolute physiologic signal value to the implantable medical device; and

means in the implantable medical device for combining the conveyed absolute physiologic signal value and ambient signal value to derive a relative physiologic signal value therefrom.

21. The system of claim 20, wherein the implantable medical device comprises an implantable monitor or therapy delivery device having implantable device memory and further comprises:

means for storing a plurality of relative physiologic signal values as relative physiologic signal value data in the implantable medical device memory.

22. The system of claim 20, wherein the implantable medical device comprises an implantable monitor or therapy delivery device having implantable device memory and data conveying means for conveying data stored in the implantable memory to an external memory device and further comprises:

means for storing a plurality of relative physiologic signal values as relative physiologic signal value data in the implantable medical device memory; and

means for activating said data conveying means to convey the relative physiological signal value data stored in the implantable memory to an external medical device.

23. The system of claim 20, wherein the implantable medical device comprises implantable device memory and a therapy delivery system for delivering a therapy to the patient and further comprises:

means for storing a predetermined number of relative physiologic signal values as relative physiologic signal value data in the implantable medical device memory; and

means for employing the relative physiologic signal values to control the delivery of the therapy by the implantable medical device.

24. The system of claim 20, wherein the implantable medical device comprises a therapy delivery system for delivering a therapy to the patient and further comprises:

controlling the delivery of the therapy by the implantable medical device as a function of the relative physiologic signal value.

25. The system of any of the preceding claims 20-24, wherein the physiologic state or condition comprises the blood pressure of the patient, the sensed absolute physiologic signal value is absolute blood pressure value, the ambient state or condition comprises barometric pressure affecting the patient and the absolute pressure value, the relative physiologic signal value is relative blood pressure value;

and the step of combining the derived absolute physiologic signal value and the conveyed ambient signal value comprises subtracting the barometric pressure value from the absolute blood pressure value.