Fungus wherein the areA gene has been modified and an areA gene from Aspergillus oryzae
First Claim
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1. An Aspergillus oryzae cell comprising a modified areA gene, wherein said modification reduces the synthesis of a functional areA gene product and wherein the modification of the areA gene is(a) a deletion of all or parts of SEQ ID NO:
- 1;
or(b) insertion of extra DNA internally into SEQ ID NO;
1.
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Abstract
A modified Aspergillus oryzae cell having an area gene which does not express a functional AreA activator, DNA sequences encoding the area gene, and method for using the cell of the invention for production of a heterologous polypeptide.
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Citations
8 Claims
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1. An Aspergillus oryzae cell comprising a modified areA gene, wherein said modification reduces the synthesis of a functional areA gene product and wherein the modification of the areA gene is
(a) a deletion of all or parts of SEQ ID NO: - 1;
or(b) insertion of extra DNA internally into SEQ ID NO;
1. - View Dependent Claims (2, 3, 4, 5, 6, 7)
- 1;
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8. An isolated DNA sequence coding for the areA gene from Aspergillus oryzae comprising SEQ ID NO:
- 1.
Specification