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Patched genes and their use for diagnostics

  • US 6,027,882 A
  • Filed: 05/31/1996
  • Issued: 02/22/2000
  • Est. Priority Date: 10/07/1994
  • Status: Expired due to Term
First Claim
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1. A method for assessing a genetic predisposition of an animal for a skin cancer, the method comprising:

  • detecting, from a sample of nucleic acid isolated from the animal, a loss-of-function mutation in a patched gene in the germline of said animal,wherein the presence of said loss-of-function mutation indicates that said animal has a genetic predisposition for basal cell carcinoma.

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