Cardiac pacing system with improved physiological event classification based on DSP

• US 6,029,087 A
• Filed: 09/22/1998
• Issued: 02/22/2000
• Est. Priority Date: 09/22/1998
• Status: Expired due to Term

• Current Assignee: Vitatron Medical BV
• Original Assignee: Vitatron Medical BV
• Inventors: Wohlgemuth, Werner Peter
• Primary Examiner(s): SCHAETZLE, KENNEDY
• Application Number:
  US09/158,566
• Time in Patent Office: 518 Days
• Field of Search: 600/509, 600/515, 600/516, 600/517, 600/518, 600/519, 600/521, 607/2, 607/4, 607/5, 607/9, 607/14, 607/26, 607/17, 128/901, 128/902
• US Class Current: 607/9
• CPC Class Codes: A61N 1/3621 for treating or preventing abnormally high heart rate
• CPC Class Codes: Y10S 128/901 Suppression of noise in electric signal

Abstract

There is provided an implantable cardiac pacing system or other cardiac monitoring system, having an enhanced capability of classifying intracardiac signals through a combination of DSP techniques and software algorithms. The implantable device has one or more DSP channels corresponding to different signals which are being monitored. Each DSP channel provides for amplification of the incoming signal; conversion from analog to digital form; digital filtering of the converted signals to provide filtered signals; operating on the filtered signals to provide slope signals; determining from the filtered and slope signals whenever an intracardiac event has been detected, e.g., R wave, P wave, etc.; and signal processing of the filtered and slope signals for a predetermined analysis interval after threshold crossing, for generating a plurality of signal parameters. The thus generated signal parameters corresponding to a signal are further operated on by a programmable algorithm to classify the detected event based upon the DSP-generated parameters. By this combination of digital signal processing and programmable software coordinated with each DSP channel, enhanced intracardiac signal classification is achieved.

Claims

1. A cardiac pacing system having a pacemaker and lead means for interconnecting said pacemaker and the patient'"'"'s heart, said pacemaker having pulse means for generating pacing pulses and control means for controlling the operation of said pacemaker, said lead means having electrode means for delivering pacing pulses to a patient'"'"'s heart and for sensing cardiac signals, said pacemaker having DSP means for amplifying and processing said cardiac signals sensed by said electrode means, and classifying means for classifying sensed cardiac signals, said DSP means comprising at least one DSP channel, said channel comprising:

conversion means for converting said received amplified signals to digital signals;

digital filter means for filtering said converted signals to provide filtered signals;

slope means for operating on said filtered signals to provide slope signals representative of the slope of said filtered signals;

sense means for determining from said filtered signals and said slope signals whenever a cardiac event is detected, and the sense time of each said detection;

analysis window means for timing out an analysis window of predetermined duration following or preceding a said sense time;

parameter means for processing said filtered signals and said slope signals during said analysis window, and for generating from said processing a plurality of respective parameters from said signals; and

wherein said pacemaker further comprises classification means for receiving said parameters from said DSP means and for classifying each said signal as a function of said parameters.

2. The system as described in claim 1, wherein said pacemaker comprises a microprocessor and said classification means comprises said microprocessor and an algorithm for operating upon said parameters.

3. The system as described in claim 2, wherein said electrode means comprises means for a plurality of respective intracardiac signals, and wherein said DSP means comprises a plurality of said channels, each channel corresponding to a respective one of said intracardiac signals, and wherein said classification means comprises a plurality of respective programmable algorithms for processing the parameters generated by each said channel.

4. The system as described in claim 1, wherein said conversion means comprises a delta-sigma modulator circuit, and wherein DSP means further comprises interconnection means for interconnecting said conversion means, said digital filter means, said slope means, said sense means and said parameter means.

5. The system as described in claim 1, wherein said parameter means comprises means for deriving four parameters from said filtered signal during each said analysis window and for deriving four respective parameters from said slope signal during each said analysis window, and wherein said classification means comprises means for classifying each said sensed signal as a function of said four signal parameters and said four slope parameters.

6. The system as described in claim 5, wherein said parameter means further comprises means for deriving a signal length as a function of comparing said filtered signals and said slope signals to predetermined threshold criteria.

7. The system as described in claim 1, wherein said sense means comprises means for comparing said filtered signals with at least one predetermined threshold and for comparing said slope signals with at least another predetermined threshold.

8. The system as described in claim 7, wherein said sense means comprises means for determining when the magnitude of said filtered signals has exceeded said one predetermined threshold and the magnitude of said slope signals has exceed said another threshold within a predetermined time interval.

9. The system as described in claim 1, wherein said parameter means comprises means operative during said analysis window for determining a minimum and maximum value for said filtered signals and for said slope signals.

10. The system as described in claim 9, wherein electrode means comprises means for sensing atrial signals, and said classifying means comprises means for distinguishing P waves and FFRS waves as a function of said minimum and maximum values for said filtered signals.

11. The system as described in claim 10, wherein said classifying means comprises means for distinguishing P waves and FFRS waves as a function of the sum of the slope maximum and minimum absolute values during a said analysis window.

12. The system as described in claim 10, wherein said classifying means comprises stored criteria relating to retrograde P waves, and comprises a software algorithm for distinguishing retrograde P waves from natural sinus P waves by comparing said minimum and maximum values to said criteria.

13. The system as described in claim 10, wherein said classifying means comprises means for distinguishing FFRWs, retrograde P waves, PACs and sinus P waves.

14. The system as described in claim 9, wherein said electrode means comprises means for sensing ventricular signals, and wherein said classifying means comprises means for classifying PVCs.

15. A cardiac pacing system, having a pulse generator for generating pacing pulses and lead means for delivering said pacing pulses to a patient'"'"'s heart and for sensing intracardiac signals from said patient'"'"'s heart, and control means for controlling the operation of said pulse generator as a function of sensed intracardiac signals, said control means comprising:

a DSP circuit having a plurality of channels, each said channel having processing means for determining when a said intracardiac signal has occurred and for processing said signal to generate a plurality of signal parameters, and each said channel being programmable and having data stored therein for use in sensing and classifying a respective type of intracardiac signal;

microprocessor means for operating on each said plurality of signal parameters to classify the signal that has occurred, said microprocessor means having a respective programmable signal algorithm corresponding to each of said DSP channels and operating means for selecting the signal algorithm corresponding to the channel which has determined a signal occurrence and for classifying the signal that has occurred; and

handling means for handling pacemaker operation in response to each type of signal which has occurred.

16. The system as described in claim 15, wherein said processing means comprises an analyzing means for each said channel, said analyzing means comprising analysis window means for timing out an analysis window during which signal parameters are obtained.

17. The system as described in claim 16, wherein said analyzing means comprises means for obtaining the slope of said signal, and means for determining maximum signal deviations for said signal and said slope during said analysis window.

18. The system as described in claim 17, wherein said analyzing means comprises signal max means for obtaining the maximum positive deviation of said signal during said analysis window and for obtaining the maximum negative deviation of said signal during said analysis window.

19. The system as described in claim 18, wherein said analyzing means comprises slope max means for obtaining the maximum positive deviation of said slope during said analysis window and for obtaining the maximum negative deviation of said signal during said analysis window.

20. The system as described in claim 17, wherein said analyzing means comprises means for obtaining up to 9 parameters reflective of a signal event, and the corresponding signal algorithm has means for classifying the event as a function of said up to 9 parameters.

21. The system as described in claim 20, wherein said analyzing means comprises means for obtaining a parameter (W) representative of the time from the first crossing of a threshold to the last threshold crossing.