Expandable stent

• US 6,033,436 A
• Filed: 02/17/1998
• Issued: 03/07/2000
• Est. Priority Date: 02/17/1998
• Status: Expired due to Term

• Current Assignee: REVA Medical Inc.
• Original Assignee: MD3 Incorporated
• Inventors: Steinke, Thomas A., Ross, Stephen O.
• Primary Examiner(s): SNOW, BRUCE EDWARD
• Application Number:
  US09/024,571
• Time in Patent Office: 749 Days
• Field of Search: 623/1, 623/12, 606/108, 606/192, 606/195, 606/194
• US Class Current: 623/1.15
• CPC Class Codes: A61F 2/91 made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
• CPC Class Codes: A61F 2/93 circumferentially expandable by using ratcheting locks
• CPC Class Codes: A61F 2250/0067 Means for introducing or releasing pharmaceutical products into the body
• CPC Class Codes: A61F 2250/0098 radio-opaque, e.g. radio-opaque markers

Abstract

The present invention provides a lumen support stent for use in an artery or any body lumen. The stent is formed from a plurality of ladder elements having elongated ribs bowed to define a circumferential arc of the tubular member and end rungs affixed to the elongated ribs. The elongated ribs of adjacent ladder elements are substantially parallel to one another and slidably engaged by the end rungs of adjacent ladder elements. Sliding of the end rungs along the circumferential arc defined by the engaged ribs creates a variable circumferential distance between the end rungs of adjacent ladder elements. Consequently, the stent has a first diameter in which the circumferential distance between end rungs of adjacent ladder elements is collapsed, and a variable second diameter in which the circumferential distance between end rungs of adjacent ladder elements is expanded.

Claims

1. A radially expandable intraluminal stent comprising:

a tubular member formed from a plurality of ladder elements, each ladder element comprising at least two elongated ribs bowed to define a circumferential arc of said tubular member and at least two end rungs affixed to the elongated ribs, said ribs and said end rungs defining a rectangular shape, wherein the elongated ribs are circumferentially disposed and substantially perpendicular to a longitudinal axis of the tubular member and the end rungs are substantially parallel to the longitudinal axis and substantially perpendicular to the elongated ribs;

wherein adjacent ladder elements overlap in a symmetrical repeating pattern, wherein an elongated rib of a first ladder element is slideably engaged by at least one end rung of an adjacent ladder element, such that sliding of the end rungs along the circumferential arc defined by the elongated ribs creates a variable circumferential distance between the end rungs of adjacent ladder elements;

the tubular member having a first diameter in which the circumferential distance between end rungs of adjacent ladder elements is collapsed; and

the tubular member having a second diameter, in which the circumferential distance between end rungs of adjacent ladder elements is expanded.

2. The expandable stent of claim 1, wherein a circumference of the tubular member is defined by a series of at least three ladder elements.

3. The expandable stent of claim 1, wherein a circumference of the tubular member is defined by a series of at least five ladder elements.

4. The expandable stent of claim 1, wherein an axial length of the tubular member is defined by at least two series of ladder elements.

5. The expandable stent of claim 4, further comprising at least one longitudinal support element, which couples the end rungs in the at least two series of ladder elements, thereby fixing the coupled series of ladder elements at a constant longitudinal distance from one another.

6. The expandable stent of claim 5, wherein said at least one longitudinal support element runs substantially parallel to the coupled end rungs and the longitudinal axis of the tubular member.

7. The expandable stent of claim 5, wherein said at least one longitudinal support element runs substantially parallel to the longitudinal axis of said tubular member and spans the entire axial length of said tubular member.

8. The expandable stent of claim 1, further comprising a plurality of locking means for maintaining the tubular member in its second, expanded diameter.

9. The expandable stent of claim 8, wherein said locking means permit adjacent end rungs to slide circumferentially apart, thereby expanding the diameter of the tubular member, but wherein said locking means prevent the end rungs from sliding back toward a more collapsed state, thereby minimizing stent recoil after deployment.

10. The expandable stent of claim 1, wherein said tubular member expands from the first, collapsed diameter to the second, expanded diameter upon application from inside the tubular member of a radially outwardly extending force.

11. The expandable stent of claim 1, wherein said tubular member is maintained under a restraint, in the first, collapsed diameter and upon removal of said restraint, the tubular member self-expands to the second, expanded diameter.

12. The expandable stent of claim 1, wherein any corners and edges are rounded, such that said comers and edges present a substantially smooth intraluminal profile.

13. The expandable stent of claim 1, wherein the ladder elements are treated with a coating agent which reduces acute thrombosis, improves long-term blood vessel patency, or addresses non-vascular issues.

14. The expandable stent of claim 13, wherein the coating agent is selected from the group consisting of parylene, heparin, hirudin, warfarin, ticlopidine, dipyridamole, GPIIb/IIIa receptor blockers, thromboxane inhibitors, serotonin antagonists, prostanoids, calcium channel blockers, PDGF antagonists, ACE inhibitors, angiopeptin, enoxaparin, colchicine, steroids, non-steroidal anti-inflammatory drugs, VEGF, adenovirus, enzymes, sterol, hydroxylase, antisense sequences, fish oils, HMG, Co-A reductase inhibitors, ibutilide fumarate, and adenylcyclase.

15. The expandable stent of claim 1, wherein at least a portion of the stent is radiopaque.

16. A radially expandable intraluminal stent comprising:

a tubular member formed from a plurality of ladder elements, each ladder element comprising at least two elongated ribs bowed to define a circumferential arc of the tubular member and at least two end rungs affixed to the elongated ribs, said ribs and said end rungs defining a parallelogram shape, wherein the end rungs are substantially parallel to one another and aligned diagonally at an angle to a longitudinal axis of the tubular member;

wherein adjacent ladder elements overlap in a symmetrical repeating pattern, wherein an elongated rib of a first ladder element is slideably engaged by at least one end rung of an adjacent ladder element, such that sliding of the end rungs along the circumferential arc defined by the elongated ribs creates a variable circumferential distance between the end rungs of adjacent ladder elements;

the tubular member having a first diameter in which the circumferential distance between end rungs of adjacent ladder elements is collapsed; and

the tubular member having a second diameter, in which the circumferential distance between end rungs of adjacent ladder elements is expanded.

17. The expandable stent of claim 16, further comprising at least one longitudinal support element, which couples the end rungs of adjacent ladder elements, thereby fixing the adjacent ladder elements at a constant longitudinal distance from one another, wherein said at least one longitudinal support element runs substantially parallel to the and rungs, being aligned diagonally at an angle to the longitudinal axis of the tubular member.

18. The expandable stent of claim 16, further comprising a longitudinal backbone, which runs at an angle to the longitudinal axis of the tubular member and spans the entire axial length of the tubular member.

19. A radially expandable intraluminal stent comprising:

a tubular member having a proximal and a distal end and a ribbed wall surface disposed between the proximal and distal ends, said ribbed wall surface being formed from a plurality of rectangular ladder elements, each ladder element having two elongated ribs which form the sides of said rectangular ladder element and two end rungs which are affixed to the elongated ribs, said ribs being bowed to define a circumferential arc of the tubular member, and said rungs being substantially parallel with the longitudinal axis of said tubular member, wherein the ribs of adjacent ladder elements, which are disposed substantially parallel to one another, overlap in a symmetrical repeating pattern, such that a rib from one ladder element is disposed between the ribs from an adjacent ladder element, and wherein said overlapping ribs are slidably engaged by the end rungs of adjacent ladder elements, such that sliding of adjacent end rungs along the circumferential arc defined by the engaged rib creates a variable circumferential distance between adjacent end rungs;

said tubular member having a first diameter in which the circumferential distance between adjacent end rungs is collapsed, thereby facilitating intraluminal delivery of the tubular member into a body lumen; and

said tubular member having a second diameter, in which the circumferential distance between adjacent end rungs is expanded, wherein the tubular member may expand said body lumen.