Bevel closure assay device housing
First Claim
1. A reclosable testing device, comprising:
- (a) abase member;
(b) a cover member;
(c) a fixed member fixed to the base member, the fixed member having an undercut edge;
(d) a hinge between the base member and the cover member;
(e) a testing element fixed to at least one of the base member or the cover member; and
(f) closure means comprising an interrupted beveled edge on the cover member, the interrupted beveled edge being supplementary to the undercut edge and being adapted to be received and retained in a closed position with the undercut edge of the fixed member in an edge-to-edge engagement, the base member, the cover member, and the fixed member being formed of a sufficiently rigid material to minimize bowing on the closure thereby to ensure that a sample for testing and the testing element come into operable contact for effecting a test, and that a force is distributed substantially evenly over the cover member, thereby further ensuring that, together with the hinge between the base member and the cover member, and with the closure means, the closure force is substantially equally distributed along the length of the closure means; and
wherein the beveled edge is interrupted with at least one uncut bridge region to increase the force required to separate the base member and cover member.
2 Assignments
0 Petitions
Accused Products
Abstract
A closure and a device for use with a closure are described. The closure includes a first member having an interrupted beveled edge, a second member having an undercut edge, and optionally a base member to which the second member is fixed. The first member is adapted to be received with the interrupted beveled edge retained by the undercut edge. A test device can include such a closure and can also include a hinge between the first and second members. Test elements, such as a chromatographic medium, an absorber, an applicator, or a sample application zone, can be disposed on the first member and/or the base member and can be brought into opposition by closing the first member with the closure. The beveled edge is interrupted by one or more uncut portions or bridges. A testing device according to the present invention can perform a number of types of immunoassays, including unidirectional assays, bidirectional assays, and assays employing a split flow path.
43 Citations
109 Claims
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1. A reclosable testing device, comprising:
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(a) abase member; (b) a cover member; (c) a fixed member fixed to the base member, the fixed member having an undercut edge; (d) a hinge between the base member and the cover member; (e) a testing element fixed to at least one of the base member or the cover member; and (f) closure means comprising an interrupted beveled edge on the cover member, the interrupted beveled edge being supplementary to the undercut edge and being adapted to be received and retained in a closed position with the undercut edge of the fixed member in an edge-to-edge engagement, the base member, the cover member, and the fixed member being formed of a sufficiently rigid material to minimize bowing on the closure thereby to ensure that a sample for testing and the testing element come into operable contact for effecting a test, and that a force is distributed substantially evenly over the cover member, thereby further ensuring that, together with the hinge between the base member and the cover member, and with the closure means, the closure force is substantially equally distributed along the length of the closure means; and
wherein the beveled edge is interrupted with at least one uncut bridge region to increase the force required to separate the base member and cover member. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17)
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18. A reclosable testing device comprising:
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(a) a base member; (b) a cover member; (c) fixed members fixed to the base member, each fixed member of the fixed members having an undercut edge; (d) a hinge between the base member and the cover member; (e) a testing element fixed to at least one of the base member or the cover member; and (f) closure means comprising interrupted beveled edges on the cover member, the beveled edges being supplementary to the undercut edges and being adapted to be received and retained in a closed position with the undercut edges of the fixed members in an edge-to-edge engagement, the base member, the cover member, and the fixed members being formed of a sufficiently rigid material to minimize bowing on the closure thereby to ensure that a sample for testing and the testing element come into operable contact for effecting a test, and that a force is distributed substantially evenly over the cover member, thereby further ensuring that, together with the hinge between the base member and the cover member, and with the closure means, the closure force is substantially equally distributed along the length of the closure means; and
wherein the beveled edges are interrupted with at least one uncut bridge region to increase the force required to separate the base member and the cover member. - View Dependent Claims (19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33)
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34. A reclosable testing device comprising:
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(a) a base member; (b) a cover member having an interrupted beveled edge; (c) a fixed member fixed to the base member, the fixed member having an undercut edge being supplementary to the interrupted beveled edge; (d) a hinge between the base member and the cover member, wherein the closure of the cover member on the base member effects engagement of the interrupted beveled edge with the undercut edge of the fixed member forming a means for closure, the interrupted beveled edge being adapted to be received and retained in a closed position in an edge-to-edge engagement with the undercut edge of the fixed member; (e) a testing element fixed to the base member and a testing element fixed to the cover member, the testing elements being in operable contact when the cover member and the base member arc closed, the base member, the cover member, and the fixed member being formed of a sufficiently rigid material to minimize bowing on the closure thereby to ensure that a sample for testing and at least one of the testing elements come into operable contact for effecting a test, and that a force is distributed substantially evenly over the cover member, thereby further ensuring that, together with the hinge between the base member and the cover member, and with the closure means formed by closure of the cover member on the base member, the closure force is substantially equally distributed along the length of the closure means; and
wherein the beveled edge is interrupted with at least one uncut bridge region to increase the force required to separate the base member and the cover member. - View Dependent Claims (35, 36, 37, 38, 39, 40, 41, 42, 43, 44)
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45. A reclosable testing device comprising:
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(a) a base member; (b) a cover member having interrupted beveled edges; (c) fixed members fixed to the base member, the fixed members having undercut edges, the undercut edges being supplementary to the interrupted beveled edges such that in a closed position of cover member and base member the interrupted beveled edges of the undercut edges are in edge-to-edge alignment forming a means for closure; (d) a hinge between the base member and the cover member; and (e) a testing element fixed to the base member and a testing element fixed to the cover member, the testing elements being in operable contact when the cover member and the base member are closed, the base member, the cover member, and each of the fixed members being formed of a sufficiently rigid material to minimize bowing on the closure, thereby to ensure that a sample for testing and at least one of the testing elements come into operable contact for effecting a test, and that a force is distributed substantially evenly over the cover member, thereby further ensuring that, together with the hinge between the base member and the cover member, and with the means for effecting closure of the cover member on the base member, the closure force is substantially equally distributed along the length of the closure means; and
wherein the beveled edge is interrupted with at least one uncut bridge region to increase the force required to separate the base member and the cover member. - View Dependent Claims (46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65)
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66. A reclosable testing device comprising:
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(a) a base member; (b) a cover member; (c) a fixed member fixed to the base member, the fixed member having an undercut edge; (d) a hinge between the base member and the cover member; (e) a testing element fixed to the base member and a testing element fixed to the cover member, at least one of the testing elements including an elongated chromatographic medium, and wherein one of the testing elements is arranged for receiving fluid and for transferring fluid to the testing element having the chromatographic medium, whereby the fluid is arranged to traverse the chromatographic medium along a defined flow path; and (f) closure means comprising an interrupted beveled edge on the cover member, the interrupted beveled edge being supplementary to the undercut edge and being adapted to be received and retained in a closed position with the undercut edge of the fixed member in a edge-to-edge engagement, the base member, the cover member, and the fixed member being formed of a sufficiently rigid material to minimize bowing on the closure, and thereby to ensure that, together with the hinge between the base member and the cover member, and with the closure means, the closure force is substantially equally distributed along the length of the closure means whereby when the interrupted beveled edge is in the closed position, the closure force is distributed substantially uniformly between the cover member and the fixed member such that the fluid is effectively transferred between the testing elements and is enabled to effectively traverse the chromatographic medium;
wherein the beveled edge is interrupted with at least one uncut bridge region to increase the force required to separate the base member and the cover member. - View Dependent Claims (67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77)
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78. A reclosable chromatographic testing device comprising:
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(a) a base member; (b) a cover member; (c) fixed members fixed to the base member, each of the fixed members having an undercut edge; (d) a hinge between the base member and the cover member; (e) a testing element fixed to the base member and a testing element fixed to the cover member, at least one of the testing elements including an elongated chromatographic medium, and wherein one of the testing elements is arranged for receiving fluid and for transferring the fluid to the testing element having the chromatographic medium, whereby the fluid is arranged to traverse the chromatographic medium along a defined flow path; and (f) closure means comprising interrupted beveled edges on the cover member, the interrupted beveled edges being supplementary to the undercut edges and being adapted to be received and retained in a closed position with the undercut edges of the fixed members in an edge-to-edge engagement, the base member, the cover member, and the fixed members being formed of a sufficiently rigid material to minimize bowing on the closure, and thereby to ensure that, together with the hinge between the base member and the cover member, and with the closure means, the closure force is substantially equally distributed along the length of the closure means whereby when the beveled edges are in the closed position, a closure force is distributed substantially uniformly between the cover member and the fixed members such that fluid is effectively transferred between the testing elements and is enabled to effectively traverse the chromatographic medium;
wherein the beveled edges are interrupted with at least one uncut bridge region to increase the force required to separate the base member and the cover member. - View Dependent Claims (79, 80, 81, 82, 83, 84, 85, 86, 87, 88, 89)
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90. A reclosable testing device comprising:
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(a) a base member; (b) a cover member having an interrupted beveled edge, the interrupted beveled edge including an exposed line of engagement; (c) a fixed member fixed to the base member, the fixed member having an undercut edge being supplementary to the interrupted beveled edge and including an exposed line of engagement; (d) a hinge between the base member and the cover member; and (e) a testing element fixed to the base member and a testing element fixed to the cover member, at least one of the testing elements being arranged for receiving fluid and for transferring fluid to the other testing element;
closure of the cover member on the base member effecting engagement of the interrupted beveled edge with the undercut edge of the fixed member, the interrupted beveled edge being adapted to be received and retained in a closed position in a edge-to-edge engagement with the undercut edge of the fixed member, forming a means for closure, the base member, the cover member and the fixed member being formed of a sufficiently rigid material to minimize bowing on the closure thereby to ensure that a sample for testing and one of the testing elements come into operable contact for effecting a test, and that a force is distributed substantially evenly over the cover member and thereby further ensuring that, together with the hinge between the base member and the cover member, and with the closure means formed by closure of the cover member on the base member, the closure force is substantially equally distributed along the length of the closure means; and
wherein the beveled edge is interrupted with at least one uncut bridge region to increase the force required to separate the base member and the cover member. - View Dependent Claims (91, 92, 93, 94, 95, 96, 97, 98, 99)
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100. A reclosable testing device comprising:
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(a) a base member; (b) a cover member having interrupted beveled edges, the interrupted beveled edges including exposed lines of engagement; (c) fixed members fixed to the base member, each of the fixed members having undercut edges, the undercut edges being supplementary to the interrupted beveled edges and including exposed lines of engagement; (d) a hinge between the base member and the cover member; and (e) a testing element fixed to the base member and a testing element fixed to the cover member, at least one of the testing elements being arranged for receiving fluid and for transferring fluid to the other testing element;
closure of the cover member on the base member effecting engagement of the interrupted beveled edges to be received and retained in edge-to-edge contact in the closed position forming means for closing with the undercut edges of the fixed members and the exposed lines of engagement of the interrupted beveled edges and the undercut edges respectively being substantially flush to the fixed members and to the cover member;
the base member, the cover member, and the fixed members being formed of a sufficiently rigid material to minimize bowing on the closure thereby to ensure that a sample for testing and one of the testing elements come into operable contact for effecting a test, and that a force is distributed substantially evenly over the cover member and thereby further insuring that, together with the hinge between the base member and the cover member, and with the means for closing formed by closure of the cover member on the base member, the closure force is substantially equally distributed along the length of the closure means, wherein the beveled edge is interrupted with at least one uncut bridge region to increase the force required to separate the base member and the cover member. - View Dependent Claims (101, 102, 103, 104, 105, 106, 107, 108, 109)
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Specification