Antisense inhibition of integrin beta 3 expression
First Claim
Patent Images
1. An antisense compound up to 30 nucleobases in length comprising at least an 8-nucleobase portion of SEQ ID NO:
- 8, 10, 11, 12, 15, 17, 18, 21, 22, 23, 24, 25, 26, 27, 30, 31, 35, 36, 38, 42, 43, 44, 46, 47, 9, 13, 20, 28, 29, 33 or 41 which inhibits the expression of human integrin beta 3, SEQ ID NO;
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Accused Products
Abstract
Antisense compounds, compositions and methods are provided for modulating the expression of integrin beta 3. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding integrin beta 3. Methods of using these compounds for modulation of integrin beta 3 expression and for treatment of diseases associated with expression of integrin beta 3 are provided.
39 Citations
10 Claims
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1. An antisense compound up to 30 nucleobases in length comprising at least an 8-nucleobase portion of SEQ ID NO:
- 8, 10, 11, 12, 15, 17, 18, 21, 22, 23, 24, 25, 26, 27, 30, 31, 35, 36, 38, 42, 43, 44, 46, 47, 9, 13, 20, 28, 29, 33 or 41 which inhibits the expression of human integrin beta 3, SEQ ID NO;
1. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10)
- 8, 10, 11, 12, 15, 17, 18, 21, 22, 23, 24, 25, 26, 27, 30, 31, 35, 36, 38, 42, 43, 44, 46, 47, 9, 13, 20, 28, 29, 33 or 41 which inhibits the expression of human integrin beta 3, SEQ ID NO;
Specification