Fiber optic based multicomponent infrared respiratory gas analyzer

• US 6,039,697 A
• Filed: 03/20/1998
• Issued: 03/21/2000
• Est. Priority Date: 03/20/1998
• Status: Expired due to Term

• Current Assignee: Datex-Ohmeda Incorporated (GE Healthcare Technologies, Inc.)
• Original Assignee: Datex-Ohmeda Incorporated (GE Healthcare Technologies, Inc.)
• Inventors: Wang, Ziyi, Wilke, Thomas A.
• Primary Examiner(s): O'Connor, Cary
• Assistant Examiner(s): Natnithithadha, Navin
• Application Number:
  US09/045,453
• Time in Patent Office: 732 Days
• Field of Search: 600/532, 600/529, 600/310, 600/473, 600/476, 250/338.1, 250/339.01, 250/339.13, 250/343
• US Class Current: 600/532
• CPC Class Codes: A61B 5/083 Measuring rate of metabolism by using breath test, e.g. measuring rate of oxygen consumption
• CPC Class Codes: A61B 5/0873 using optical means
• CPC Class Codes: A61B 5/097 Devices for facilitating collection of breath or for directing breath into or through measuring devices
• CPC Class Codes: G01N 21/3504 for analysing gases, e.g. multi-gas analysis

Abstract

A novel respiratory gas analyzer employs optical fibers to facilitate in-stream, multiple component infrared analysis. In one embodiment, the analyzer (10) includes an infrared source (12), entrance optics (14), a sample chamber (20), exit optics (24) and a detector assembly (28). One or both of the entrance optics (14) and exit optics (24) includes infrared optical fibers. In this manner, the source (12) and or detector assembly (28) can be located away from the patient (22) as may be desired. In addition, the fiber optic implementation reduces system complexity and optical alignment concerns.

Claims

1. An apparatus for monitoring the composition of a main respiratory gas stream of a patient, said apparatus comprising:

a broad band infrared source capable of producing infrared light having a spectral content distributed at least across a wavelength range from about 4 microns to about 8 microns;

means for detecting infrared signals at a plurality of wavelengths within said wavelength range; and

means for transmitting light between said broad band infrared source and said means for detecting, said light being transmitted at least partially through a respiratory gas conduit outside the patient such that said main respiratory gas stream at said patient can be analyzed free from the need to divert a side stream therefrom for purposes of composition analysis, the main respiratory gas the conduit being adapted for flow of the main respiratory gas stream therethrough, said means for transmitting including fiber optics for transmitting infrared light within said wavelength range.

2. An apparatus according to claim 1, wherein said means for transmitting includes a fiber optics light guide capable of transmitting infrared light between said source and said conduit.

3. An apparatus according to claim 1, wherein said means for transmitting includes a fiber optics light guide capable of transmitting infrared light between said conduit and said means for detecting.

4. An apparatus according to claim 3, wherein:

said conduit includes a wall portion outside said patient;

said wall portion includes first and second opposed windows which allow infrared light transmission across said conduit; and

said means for transmitting light transmits light across said conduit through said windows.

5. An apparatus according to claim 1, wherein:

said conduit includes a wall portion outside said patient, said wall portion including a window;

said means for transmitting includes an end portion and means for reflecting infrared light, said means for reflecting spaced apart from said end portion so as to provide a two-directional pathway for light transmission between said end portion and said means for reflecting, said end portion adapted for releasable engagement with said wall portion at said window such that said means for reflecting is positioned inside said conduit; and

said means for transmitting transmits light between said broad band infrared source and said means for reflecting and between said means for reflecting and said means for detecting.

6. An apparatus according to claim 1, wherein:

said conduit includes a wall portion outside said patient, said wall portion including first and second opposed windows which allow infrared light transmission across said conduit;

said means for transmitting including support means for supporting, in predetermined spatial relationship, an end portion and means for reflecting infrared light, said means for reflecting spaced apart from said end portion so as to provide a two-directional pathway for light transmission through said conduit via said windows, said support means adapted for engaging with said conduit adjacent said wall portion such that said end means is positioned adjacent said first window and said means for reflecting is positioned adjacent said second window; and

said means for transmitting transmits light from said broad band infrared source through said first window to said means for reflecting and from said means for reflecting to said means for detecting.

7. An apparatus according to claim 1, wherein:

said conduit includes a wall portion outside said patient, said wall portion including at least one window; and

said means for transmitting includes an unshielded fiber optics portion which is insertable into said conduit through the at least one window, said unshielded portion capable of allowing interaction of infrared light with said gas in said conduit.

8. An apparatus according to claim 1, wherein said infrared source produces light having a continuum of infrared wavelengths.

9. An apparatus according to claim 8, wherein said continuum extends between about 4 microns and about 10 microns.

10. An apparatus according to claim 8, wherein said continuum extends between about 2 microns and about 12 microns.

11. An apparatus according to claim 1, wherein said means for detecting comprises:

at least one filter capable of filtering incident light on a wavelength dependent basis; and

at least one detector element capable of receiving filtered light from said filter.

12. An apparatus according to claim 1, further comprising an analyzer for providing information regarding the concentration of carbon dioxide and at least one of nitrous oxide, halothane, enflurane, sevoflurane, desflurane, and isoflurane.

13. An apparatus for monitoring the composition of a respiratory gas stream of a patient, said apparatus comprising:

a broad band infrared source capable of producing infrared light having a spectral content distributed at least across a wavelength range from about 4 microns to about 8 microns;

means for detecting infrared signals at a plurality of wavelengths within said wavelength range;

means for transmitting light between said broad band infrared source and said means for detecting, said light being transmitted at least partially through a respiratory gas conduit outside the conduit being adapted for flow of the respiratory gas stream therethrough, said means for transmitting including fiber optics for transmitting infrared light within said wavelength range; and

a reference light path including fiber optics, and wherein said means for detecting infrared signals includes means for comparing infrared signals received via said means for transmitting to signals received via said reference light path.

14. An apparatus for monitoring the composition of a main respiratory gas stream of a patient, said apparatus comprising:

an infrared light source;

a detector assembly capable of detecting infrared light having wavelengths produced by said source, said detector assembly including means for separately detecting infrared light within a plurality of infrared wavelength bands, each said band having a unique spectral content; and

transmission means for transmitting infrared light from said infrared source between said infrared source and said means for detecting, said transmission means including fiber optics for transmitting said infrared light wherein said infrared light is transmitted at least partly through a main respiratory gas conduit outside said patient such that said main respiratory gas stream at said patient can be analyzed free from the need to divert a side stream therefrom for purposes of composition analysis, said main respiratory gas conduit having a wall portion for transmitting infrared light produced by said infrared source.

15. An apparatus according to claim 14, wherein said infrared light source is a broad band infrared source having a spectral content distributed at least across a wavelength range from about 4 microns to about 8 microns.

16. An apparatus according to claim 14, further comprising means for reflecting infrared light, said means for reflecting being positionable within said conduit.

17. An apparatus according to claim 14, wherein:

said conduit includes two opposed windows for transmitting light; and

said apparatus further comprises means for reflecting infrared light, said means for reflecting being positionable outside said conduit adjacent one of said windows, wherein light is transmitted through said wall portion and said gas inside said conduit and reflected back through said wall portion and said gas.

18. An apparatus for monitoring multiple components in a main respiratory gas stream of a patient, said apparatus comprising:

means for receiving said main respiratory gas stream, said means adapted to allow said main respiratory gas stream to flow therethrough and also adapted for infrared spectroscopy of a gas located therein such that said main respiratory gas stream at said patient can be analyzed free from the need to divert a side stream therefrom for purposes of composition analysis;

an infrared source;

means for detecting infrared light transmitted through said means for receiving and said respiratory gas stream and for characterizing said respiratory gas stream relative to multiple gaseous components present in said respiratory gas stream;

means for transmitting light between said infrared source and said means for receiving and between said means for receiving and said means for detecting, said means for transmitting including fiber optics operative to transmit infrared light.

19. An apparatus according to claim 18, wherein said infrared source is a broad band source having a spectral content distributed at least across a wavelength range from about 4 microns to about 8 microns.

20. An apparatus according to claim 18, wherein said means for detecting is capable of detecting infrared signals at multiple wavelengths indicative of quantities of said multiple components present in said means for receiving.

21. An apparatus according to claim 18, wherein:

said means for transmitting includes an infrared fiber optics light guide having an unshielded portion inside a respiratory gas conduit;

said means for detecting includes means for detecting said infrared light after transmission through said fiber optics light guide and determining composition information based on interactions with said respiratory gas at an interface between said light guide and said gas.

22. An apparatus according to claim 21, wherein said means for detecting includes means for performing Fourier transform analysis on light transmitted through said fiber optics light guide.

23. An apparatus according to claim 21, further comprising means for modulating light from said infrared source to provide an infrared signal for transmission via said means for transmitting.

24. An apparatus for monitoring the composition of a main respiratory gas stream of a patient, said apparatus comprising:

probe means for transmitting infrared light to and from a main respiratory gas conduit for receiving said main respiratory gas stream such that said main respiratory gas stream at said patient can be analyzed free from the need to divert a side stream therefrom for purposes of composition analysis, said probe means supporting first means for transmitting said infrared light into said main respiratory gas conduit and second means for receiving the infrared light transmitted into said main respiratory gas conduit;

said probe means including infrared fiber optics for transmitting said infrared light and coupling means for coupling said probe means to said main respiratory gas conduit such that said infrared light is transmitted through said main respiratory gas stream and returned from said main respiratory gas conduit by said probe means for use in analysis.

25. An apparatus according to claim 24, wherein said probe means includes means for reflecting infrared light and having a two-directional light path between said fiber optics and said reflecting means.

26. An apparatus according to claim 24, wherein:

said probe means includes an unshielded fiber optics light guide, said unshielded light guide being positionable substantially inside said main respiratory gas conduit.

27. A method for monitoring multiple components in a main respiratory gas stream of a patient, said method comprising:

receiving said main respiratory gas stream in a conduit adapted to allow said main respiratory gas stream to flow therethrough such that said main respiratory gas stream at said patient can be analyzed free from the need to divert a side stream therefrom for purposes of composition analysis;

transmitting light between an infrared source and said conduit and between said conduit and a means for detecting, said transmission being via means for transmitting including fiber optics operative to transmit infrared light; and

detecting infrared light transmitted through said means for receiving and said respiratory gas stream and analyzing said detected infrared light relative to multiple gaseous components.

28. A method according to claim 27, wherein:

said transmitting step includes modulating said infrared light to provide a modulated optical signal and transmitting said modulated signal via an infrared fiber optics light guide having an unshielded portion inside said conduit.

29. A method according to claim 27, wherein said analyzing step includes performing Fourier transform analysis on light transmitted through said fiber optics light guide.

31. A method according to claim 27, wherein said step of transmitting comprises:

providing infrared light having a spectral content distributed at least across a wavelength range from about 4 microns to about 8 microns.

32. A method according to claim 27, wherein said transmitting step comprises:

transmitting light through a wall portion of said conduit, said wall portion including first and second opposed windows which allow infrared light transmission across said conduit.

33. A method according to claim 27, wherein said transmitting step comprises:

transmitting light through a wall portion of said conduit;

reflecting said transmitted light with a reflecting means; and

receiving said reflected light for transmission to said detecting means.

34. A method according to claim 27, wherein said detecting step comprises:

filtering light received by said means for detecting, said filtering being on a wavelength dependent basis; and

detecting filtered light received through said filter.

35. A method according to claim 27, wherein:

said respiratory gas comprises carbon dioxide and at least one component selected from nitrous oxide, halothane, enflurane, sevoflurane, desflurane, and isoflurane; and

said analyzing step comprises providing information regarding the concentration of said at least one component.

30. A method for monitoring multiple components in a respiratory gas stream of a patient, said comprising:

receiving said respiratory gas stream in a conduit adapted to allow said respiratory gas stream to flow therethrough;

transmitting light between an infrared source and between said conduit and a means for detecting, said transmission being via means for transmitting includes fiber optics operative to transmit infrared light;

detecting infrared light transmitted through said means for receiving and said respiratory gas stream and analyzing said detected infrared light relative to multiple gaseous components; and

comparing light transmitted through said means for receiving with a reference light measurement.

36. A method according to claim 30, wherein said step of comparing comprises:

providing a reference light path including fiber optics;

detecting reference infrared signals transmitted over said reference light path; and

comparing infrared signals received via said means for transmitting to signals received via said reference light path.