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Method and means for magnetic particle specific binding assay

  • US 6,040,192 A
  • Filed: 08/26/1997
  • Issued: 03/21/2000
  • Est. Priority Date: 02/01/1993
  • Status: Expired due to Term
First Claim
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1. A method for determining the presence of an analyte in a sample, the method comprising the steps of:

  • a. inserting a sample to be tested into a reaction vessel;

    b. inserting solid magnetic particles coated with separating reagent into said reaction vessel to react with the sample;

    c. removing said particles from said reaction vessel by inserting a magnet-equipped remover into said reacting vessel, wherein said particles adhere to said remover;

    d. inserting the remover containing the particles into a measuring vessel wherein at least one of said reaction and measuring vessels contains a medium and agitating the medium by moving said remover vertically while said particles adhere to said remover to improve adherence of said particles;

    e. measuring the reaction between the separating reagent and the sample; and

    f. determining the presence of the analyte.

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