Insulated catheter for selective organ perfusion
First Claim
1. An apparatus for selective organ hypothermia by perfusion, said apparatus comprising:
- a chiller;
a flexible elongated supply catheter, said supply catheter having a proximal end attachable to an inlet of said chiller, said supply catheter having a distal end percutaneously insertable into an artery of a patient;
a flexible elongated delivery catheter, said delivery catheter having a proximal end attachable to an outlet of said chiller, said delivery catheter having sufficient length and sufficiently small diameter to be insertable percutaneously through a vascular system of a patient to a feeder artery of a selected organ of a patient, said delivery catheter having a lumen for flow of cooled blood from said chiller to a feeder artery of a selected organ of a patient;
an insulating layer in said delivery catheter between said blood lumen and the outer surface of said delivery catheter; and
a blood outlet formed in said blood lumen, near a distal end of said delivery catheter.
12 Assignments
0 Petitions
Accused Products
Abstract
A method and apparatus for performing hypothermia of a selected organ without significant effect on surrounding organs or other tissues, by perfusion of the organ with blood cooled externally from the body of the patient. A flexible supply catheter is inserted percutaneously into an artery. Blood from the supply catheter is cooled in a finned tube heat exchanger or a fluid bath. A flexible delivery catheter is inserted percutaneously through the vascular system of the patient to place the distal end of the catheter in an artery feeding the selected organ. An occlusion device is expanded to occlude the feeder artery at a point proximal to the distal end of the delivery catheter. Cooled blood from the chiller is pumped through the delivery catheter to an outlet near the distal end of the catheter, to cool the selected organ, distal to the tip of the delivery catheter.
-
Citations
22 Claims
-
1. An apparatus for selective organ hypothermia by perfusion, said apparatus comprising:
-
a chiller; a flexible elongated supply catheter, said supply catheter having a proximal end attachable to an inlet of said chiller, said supply catheter having a distal end percutaneously insertable into an artery of a patient; a flexible elongated delivery catheter, said delivery catheter having a proximal end attachable to an outlet of said chiller, said delivery catheter having sufficient length and sufficiently small diameter to be insertable percutaneously through a vascular system of a patient to a feeder artery of a selected organ of a patient, said delivery catheter having a lumen for flow of cooled blood from said chiller to a feeder artery of a selected organ of a patient; an insulating layer in said delivery catheter between said blood lumen and the outer surface of said delivery catheter; and a blood outlet formed in said blood lumen, near a distal end of said delivery catheter. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15)
-
-
16. An apparatus for selective organ hypothermia by perfusion, said apparatus comprising:
-
a chiller; a flexible elongated supply catheter, said supply catheter having a proximal end connected in fluid flow communication with an inlet of said chiller, said supply catheter having a distal end percutaneously insertable into an artery of a patient; a pump connected to said supply catheter; a flexible elongated delivery catheter, said delivery catheter having a proximal end connected in fluid flow communication with an outlet of said chiller, said delivery catheter having sufficient length and sufficiently small diameter to be insertable percutaneously through a vascular system of a patient to a feeder artery of a selected organ of a patient, said delivery catheter having a lumen for flow of cooled blood from said chiller to a feeder artery of a selected organ of a patient; an insulating layer in said delivery catheter between said blood lumen and the outer surface of said delivery catheter; a blood outlet formed in said blood lumen, near a distal end of said delivery catheter; and an occlusion device formed on said distal end of said delivery catheter, said occlusion device being selectively expandable to occlude the feeder artery of the selected organ, at a point proximal to said blood outlet.
-
-
17. A method for selective organ hypothermia by perfusion, said method comprising:
-
providing a chiller, a flexible supply catheter connected to an inlet of said chiller, and a flexible delivery catheter connected to an outlet of said chiller, said delivery catheter having a blood lumen, an insulating layer around said lumen, and a blood outlet adjacent its distal end; percutaneously inserting a distal end of said supply catheter into an artery of a patient; percutaneously inserting a distal end of said delivery catheter into an easily accessible artery near the skin of the patient; passing said delivery catheter through the vascular system of the patient to place said distal end of said delivery catheter in a feeder artery of a selected organ; flowing blood from the supply artery through said supply catheter, said chiller, and said delivery catheter, to the feeder artery of the selected organ; and cooling blood flowing through said chiller, and maintaining the blood flow in said delivery catheter at a lowered temperature, to enable said blood to flow distally into the selected organ and cool the organ. - View Dependent Claims (18, 19)
-
-
20. A method for selective organ hypothermia by perfusion, said method comprising:
-
providing a supply catheter and a flexible insulated delivery catheter; introducing a distal end of said supply catheter into an artery of a patient; introducing said insulated catheter into the vascular system of a patient to place a distal end of said insulated catheter in a feeding artery of an organ of the patient; withdrawing blood from said patient through said supply catheter; cooling said blood in a chiller; delivering said cooled blood to said feeding artery via said insulated delivery catheter; and cooling said organ by flow of said cooled blood through said feeding artery.
-
-
21. A method for selective brain hypothermia by perfusion, said method comprising:
-
providing a supply catheter and a flexible insulated delivery catheter; introducing a distal end of said supply catheter into an artery of a patient; introducing said insulated catheter into the vascular system of a patient to place a distal end of said insulated catheter in a carotid artery of the patient; withdrawing blood from said patient through said supply catheter; cooling said blood in a chiller; delivering said cooled blood to said carotid artery via said insulated delivery catheter; and cooling the brain of the patient by flow of said cooled blood through said carotid artery.
-
-
22. A method for selective hypothermia of the heart of a patient, by perfusion, said method comprising:
-
providing a supply catheter and a flexible insulated delivery catheter; introducing a distal end of said supply catheter into an artery of a patient; introducing said insulated catheter into the vascular system of a patient to place a distal end of said insulated catheter in a feeding artery of the heart of the patient; withdrawing blood from said patient through said supply catheter; cooling said blood in a chiller; delivering said cooled blood to said feeding artery via said insulated delivery catheter; and cooling the heart of the patient by flow of said cooled blood through said feeding artery.
-
Specification