Non-intravascular infusion access device
First Claim
1. A non-intravascular infusion access device for long-term continuous infusion of a therapeutic agent into the body, comprising:
- an elongate tubular porous membrane having a closed end and an open end, said membrane made of a substantially nonexpandable biocompatible material suitable for implantation within a non-intravascular location inside the body and having pores sized to allow the passage of the therapeutic agent through said membrane while preventing the passage of a member selected from the group consisting of bacteria and viruses;
a conducting tubing having first and second open ends, said conducting tubing sized to permit infusion therethrough of a fluid containing the therapeutic agent, said open end of said tubular porous membrane attached to and in fluid communication with said first open end of said tubing whereby fluid infused through said conducting tubing is caused to flow through said porous membrane;
an infusion delivery system including a fluid source containing the therapeutic agent; and
a means for connecting the second open end of said conducting tubing to the infusion delivery system.
3 Assignments
0 Petitions
Accused Products
Abstract
A non-intravascular infusion access device and method for long-term continuous infusion of drugs. The infusion access device includes a porous membrane made of a material which is biocompatible for long-term patency inside the body. The porous membrane is connected to a conducting tubing which exits from the body and is connected to a drug infusion system. At the exit site is a cuff of porous material. The cuff serves to anchor the access device in position as the surrounding body tissue grows back around the cuff. There are also two small suture retainers for stabilizing the position of the access device relative until tissue ingrowth occurs in and around the cuff.
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Citations
16 Claims
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1. A non-intravascular infusion access device for long-term continuous infusion of a therapeutic agent into the body, comprising:
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an elongate tubular porous membrane having a closed end and an open end, said membrane made of a substantially nonexpandable biocompatible material suitable for implantation within a non-intravascular location inside the body and having pores sized to allow the passage of the therapeutic agent through said membrane while preventing the passage of a member selected from the group consisting of bacteria and viruses; a conducting tubing having first and second open ends, said conducting tubing sized to permit infusion therethrough of a fluid containing the therapeutic agent, said open end of said tubular porous membrane attached to and in fluid communication with said first open end of said tubing whereby fluid infused through said conducting tubing is caused to flow through said porous membrane; an infusion delivery system including a fluid source containing the therapeutic agent; and a means for connecting the second open end of said conducting tubing to the infusion delivery system. - View Dependent Claims (2, 3, 4, 5, 6, 7)
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8. The non-intravascular infusion access device of clam 1 wherein said porous membrane is formed of a copolymer of polyacrylonitrile and polyvinyl chloride.
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9. A kit for providing long-term continuous infusion of a therapeutic agent into a non-intravascular body location, comprising:
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(a) an elongate tubular porous membrane having a closed end and an open end, said membrane made of a substantially nonexpandable biocompatible material suitable for implantation within a non-intravascular location inside the body and having pores sized to allow the passage of the therapeutic agent through said membrane while preventing the passage of a member selected from the group consisting of bacteria and viruses; (b) a conducting tubing having one end connected in fluid communication with said open end of said porous membrane and sized to permit infusion therethrough of a fluid containing the therapeutic agent; (c) an infusion system including a fluid source containing the therapeutic agent configured for connection to said conducting tubing opposite said one end; and (d) an introducer having a passageway sized to slidably receive therethrough at least that portion of said non-intravascular infusion access device including said porous membrane. - View Dependent Claims (10)
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11. An infusion access device for long-term continuous infusion of insulin into a subcutaneous space within the body, comprising:
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an elongate tubular porous membrane having a closed distal and open proximal end, said porous membrane formed of a material compatible for implantation within a subcutaneous body space and having pores sized to allow the passage of insulin through said membrane; a conducting tubing having one end connected to the proximal open end of said porous membrane in fluid communication therethrough, said conducting tubing sized to permit infusion therethrough of a fluid containing the therapeutic agent; and an adaptor connecting said proximal open end of said conducting tubing to an insulin infusion system.
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12. A method for continuous long-term infusion of a therapeutic agent into the body, comprising the acts of:
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providing an infusion access device including an elongate tubular porous membrane and a fluid conducting tube; implanting said porous membrane into a non-intravascular body location; connecting said infusion access device to an externally located fluid source containing a therapeutic agent whereby the source is in fluid communication with the fluid conducting tube; and infusing a fluid containing the therapeutic agent from said fluid source through said porous membrane; wherein the elongate tubular porous membrane has a closed end and an open end, said membrane made of a substantially nonexpandable biocompatible material suitable for implantation within a non-intravascular location inside the body and having pores sized to allow the passage of the therapeutic agent through said membrane while preventing the passage of a member selected from the group consisting of bacteria and viruses; and wherein the conducting tubing has first and second open ends, said conducting tubing sized to permit infusion therethrough of a fluid containing the therapeutic agent, said open end of said tubular porous membrane attached to and in fluid communication with said first open end of said tubing whereby fluid infused through said conducting tubing is caused to flow through said porous membrane. - View Dependent Claims (13, 14, 15, 16)
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Specification