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Drug-releasing coatings for medical devices

  • US 6,042,875 A
  • Filed: 03/02/1999
  • Issued: 03/28/2000
  • Est. Priority Date: 04/30/1997
  • Status: Expired due to Fees
First Claim
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1. A method of making a medical device having at least a portion for insertion or implantation into the body of a patient, wherein the portion has a surface which is adapted for exposure to body tissue of the patient and wherein at least a part of the surface is covered with a coating to release at least one biologically active material therefrom, the method comprising:

  • a) forming a reservoir layer over the surface by applying a reservoir layer composition comprising a polymer and a biologically active material andb) forming an outer layer over the reservoir layer by applying an outer layer composition comprising an ionic surfactant complexed to the biologically active material.

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