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Integrated nucleic acid diagnostic device

  • US 6,043,080 A
  • Filed: 12/11/1998
  • Issued: 03/28/2000
  • Est. Priority Date: 06/29/1995
  • Status: Expired due to Term
First Claim
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1. A miniature analytical device, comprising:

  • a body having at least first, second and third chambers in fluid communication within said body;

    said first chamber having disposed therein at least one reagent for amplifying a nucleic acid segment within a sample,said second chamber for fragmenting said nucleic acid segmentand said third chamber having an array of nucleic acid probes disposed therein, said array including a plurality of different nucleic acid sequences coupled to a surface of a single substrate, each of said plurality of different nucleic acid sequences being coupled to said surface in a different, known location.

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