Device and evaluation procedure for the depth-selective, noninvasive detection of the blood flow and/or intra and/or extra-corporeally flowing liquids in biological tissue
First Claim
1. A device (10) for a non-invasive detection of one of a blood flow and intracorporeally and extracorporeally flowing liquids in one of a human and animal tissue (12);
- said device comprisinga coherent, monochromatic source of light (14) including a laser, for emission of a plurality of photons into the tissue (12), through a first area (16) of skin (18) covering the tissue (12),at least one detector (20) for registering the photons reemerging from one of a plurality of superficial areas (22) of the skin (18) whereby the plurality of superficial areas (22) are located at different distances from the first area (16); and
a detection means for selectively detecting a blood flow a selective depth below said skin.
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Accused Products
Abstract
A device and an evaluation procedure for the depth-selective, non-invasive detection of the blood flow and/or intra- and/or extracorporeally flowing liquids in biological tissue are described whereby photons of a coherent, monochromatic source of light are entered into the tissue through a first area, photons reemerging from the tissue at different distances from this first area are detected with respect to their frequency and number, or intensity, and, from this information, i.e. frequency and/or number, or intensity, and/or reemerging location, conclusions about the relative modification of the flow amount and/or speed and/or location of the blood flow and/or the intra- and/or extracorporeally flowing liquids in the tissue are drawn with the help of an evaluation program or algorithm.
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Citations
20 Claims
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1. A device (10) for a non-invasive detection of one of a blood flow and intracorporeally and extracorporeally flowing liquids in one of a human and animal tissue (12);
- said device comprising
a coherent, monochromatic source of light (14) including a laser, for emission of a plurality of photons into the tissue (12), through a first area (16) of skin (18) covering the tissue (12), at least one detector (20) for registering the photons reemerging from one of a plurality of superficial areas (22) of the skin (18) whereby the plurality of superficial areas (22) are located at different distances from the first area (16); and a detection means for selectively detecting a blood flow a selective depth below said skin. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11)
- said device comprising
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12. A device (10) for a non-invasive detection of one of a blood flow and intracorporeally and extracorporeally flowing liquids in one of a human and animal tissue (12);
- said device comprising
a coherent, monochromatic source of light (14) including a laser, for emission of a plurality of photons into the tissue (12), through a first area (16) of skin (18) covering the tissue (12), at least one detector (20) for registering the photons reemerging from one of a plurality of superficial areas (22) of the skin (18) whereby the plurality of superficial areas (22) are located at different distances from the first area (16); and a detection means for selectively detecting a blood flow a selective depth below said skin, wherein said plurality of superficial areas (22) are serially arranged in pairs disposed on opposing sides of a line (100) extending from said first area and a corresponding pair of said plurality of detectors (20) are resperctivley arranged proximate said pairs of superficial areas and essentially in series, whereby each pair of superficial areas has a predetermined distance from the first area (16) and distances between neighboring pairs of superficial areas are equidistant.
- said device comprising
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13. A device (10) for a non-invasive detection of one of a blood flow and intracorporeally and extracorporeally flowing liquids in one of a human and animal tissue (12);
- said device comprising
a coherent, monochromatic source of light (14) including a laser, for emission of a plurality of photons into the tissue (12), through a first area (16) of skin (18) covering the tissue (12), at least one detector (20) for registering the photons reemerging from one of a plurality of superficial areas (22) of the skin (18) whereby the plurality of superficial areas (22) are located at different distances from the first area (16); and a detection means for selectively detecting a blood flow a selective depth below said skin, wherein a plurality of signals of the detectors (20) are submitted to an adaptive filter function (52) as well as to a cepstrum analysis function (78).
- said device comprising
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14. An evaluation procedure for detecting one of a blood flow and an intracorporeally and an extracorporeally flowing liquid in one of a human, and animal biological tissue (12) at a selective depth below said tissue, comprising the steps of:
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entering photons of a coherent, monochromatic source of light (14) into the biological tissue (12) of a first area (16), said photons reemerging at a plurality of superficial areas of different distances from said first area (16);
wherein each of said superficial area corresponds to a specific depth of said one of said blood flow and flowing liquids;determining said specific depth of each of said superficial areas by a known relationship with a distance between said superficial areas and said first area; detecting said reemerging photons with respect to one of a frequency and a number and an intensity of said photons, and generating, by using an evaluation program conclusions about a relative modification of one of an amount of speed and a location of one of the blood flow and flowing liquids flowing in the tissue (12) at said specific depth from one of said frequency and number and intensity of said reemerging photons. - View Dependent Claims (15, 16, 17, 18)
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19. An evaluation procedure for detecting one of a blood flow and an intracorporeally and an extracorporeally flowing liquid in one of a human, and animal biological tissue (12), comprising the steps of:
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entering photons of a coherent, monochromatic source of light (14) into the biological tissue (12) of a first area (16), said photons reemerging at different distances from said first area (16) are detected with respect to one of a frequency and a number and an intensity of said photons, generating a plurality of signals representative of at least one of said frequency and said number and said intensity of said reemerging photons, and generating, by using an evaluation program conclusions about a relative modification of one of an amount of speed and a location of one of the blood flow and flowing liquids flowing in the tissue (12) from one of said frequency and number and intensity of said reemerging photons, wherein said step of entering photons comprises a source of light (14) with a high coherence length being higher than 10 cm, wherein the detected signals of two superficial areas (22) are submitted to an adaptive filter function (52) for determination of blood flow a selective depth below the skin.
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20. A device (10) for a non-invasive detection of a blood flow in a human comprising:
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a coherent, monochromatic source of light (14) including a laser for emission of a plurality of photons into the tissue (12), through a first area (16) of skin (18) covering the tissue (12), a plurality of opposing pairs of detectors serially positioned discretely along a line extending from said first area adjacent a corresponding superficial area of skin surface of said human;
said detectors registering the photons reemerging from said skin at said superficial areas (22) of the skin (18); anda detection means for selectively detecting said blood flow a specific depth below said skin, wherein said specific depth corresponds to said distance of said superficial area to said first area.
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Specification