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Method and device for measuring blood coagulation or lysis by viscosity changes

  • US 6,046,051 A
  • Filed: 06/27/1997
  • Issued: 04/04/2000
  • Est. Priority Date: 06/27/1997
  • Status: Expired due to Term
First Claim
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1. A single-use electronic device for performing a coagulation or lysis assay of a blood sample, the device comprising:

  • a housing having an exterior surface and defining an interior area;

    means for receiving the blood sample through the housing into the interior area;

    a non-porous substrate positioned within the interior area for receiving the blood sample thereon;

    a reagent for accelerating the coagulation of the blood sample positioned on the substrate and in contact with the blood sample;

    an electroactive species positioned on the substrate and in contact with the blood sample;

    means for measuring the viscosity of the blood sample and generating an electrical signal which correlates to a curve of a coagulation or lysis assay;

    processing means being positioned within the interior area and connected to the measuring means for receiving and converting the electrical signal into a digital output corresponding to the coagulation or lysis assay using assay calibration information stored in the processing means; and

    display means for visually displaying the digital output external to the housing, the display means being connected to the processing means.

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