Vascular impedance measurement instrument

• US 6,048,318 A
• Filed: 01/26/1999
• Issued: 04/11/2000
• Est. Priority Date: 12/28/1990
• Status: Expired due to Term

• Current Assignee: Hypertension Diagnostics, Inc.
• Original Assignee: Hypertension Diagnostics, Inc.
• Inventors: Cohn, Jay N., Finkelstein, Stanley M., Chesney, Charles F.
• Primary Examiner(s): Schaetzle, Kennedy J.
• Application Number:
  US09/237,444
• Time in Patent Office: 441 Days
• Field of Search: 600/483, 600/485, 600/500, 600/504, 600/526, 600/481, 128/920
• US Class Current: 600/483
• CPC Class Codes: A61B 5/02007 Evaluating blood vessel condition, e.g. elasticity, compliance
• CPC Class Codes: A61B 5/021 Measuring pressure in heart or blood vessels A61B5/0205 takes precedence
• CPC Class Codes: A61B 5/029 Measuring or recording blood output from the heart, e.g. minute volume A61B8/065 takes precedence
• CPC Class Codes: G09B 23/28 for medicine
• CPC Class Codes: Y10S 128/92 Computer assisted medical diagnostics

Abstract

A vascular impedance measurement instrument includes a transducer to obtain a digitized arterial blood pressure waveform. The digitized data is used to determine cardiac output, and to subsequently obtain measurements of impedance parameters using the modified Windkessel model of the arterial system. The instrument is used as an aid in diagnosing, treating and monitoring patients with cardiovascular disease.

Claims

1. A method for measuring vascular impedance properties from the blood pressure waveform of a patient from the measurement of the arterial blood pressure waveform, the waveform containing heart beat signals, comprising:

measuring an arterial blood pressure of a patient;

determining an ejection time of the heart of the patient;

processing said ejection time and other patient data to determine a cardiac output measurement value for the patient from at least said ejection time and other patient data; and

processing the arterial blood pressure waveform and the cardiac output value to determine for the patient one or more parameters of a vascular impedance model, the parameters being measures of vascular impedance properties.

2. A method according to claim 1 further wherein the measures of vascular impedance properties include a measure of compliance of the patient'"'"'s blood vessels.

3. A method according to claim 1 further wherein the measures of vascular impedance properties include a measure of resistance of the patient'"'"'s blood vessels to the flow of blood.

4. A method for measuring vascular impedance properties from the blood pressure waveform of a patient, comprising:

processing a digital representation of an arterial blood pressure waveform of a patient to determine a cardiac output value for the patient; and

processing the digital representation and the cardiac output value to determine for the patient one or more measures of vascular impedance properties.