Non-invasive acoustic screening device for coronary stenosis

• US 6,048,319 A
• Filed: 10/01/1998
• Issued: 04/11/2000
• Est. Priority Date: 10/01/1998
• Status: Expired due to Fees

• Current Assignee: Integrated Medical Systems Incorporated (Steris Corporation)
• Original Assignee: Integrated Medical Systems Incorporated (Steris Corporation)
• Inventors: Chandraratna, Premindra A., Hudgins, Lonnie H.
• Primary Examiner(s): Kamm, William E.
• Application Number:
  US09/164,618
• Time in Patent Office: 558 Days
• Field of Search: 600/508, 600/528
• US Class Current: 600/528
• CPC Class Codes: A61B 7/04 Electric stethoscopes microphones, acoustic transducers therefor H04R

Abstract

Method and apparatus for detecting coronary stenosis. The apparatus comprises an acoustic sensor and a microcomputer that identifies the standard S1 and S2 heart sounds, heart rate, and determines the diastolic interval of the subject and thereafter estimates the acoustic energy levels within a 2 octave band around approximately 20 Hz during diastole. Based upon such estimation, a diagnosis can be rendered as to the presence and degree of stenosis from the coronary artery.

Claims

1. A system for detecting coronary artery disease from an acoustical signal generated from a heartbeat of a human subject, said apparatus comprising:

a) a microphone for converting the acoustical signal generated from said heartbeat into an electrical signal;

b) a computer for processing said electrical signal to identify a first sound corresponding to the closure of the atrioventricular valves and the contraction of the ventricles, and a second sound corresponding to the closure of the aortic and pulmonary valves, and thereafter determining the interval between said first and second cardiac sounds; and

c) wherein said computer is further operative to determine the heart rate of said human and compare the same to said interval between said first and second cardiac sounds to thus quantify the diastolic energy emanating from the coronary artery during diastole and thereafter comparing said diastolic energy to baseline parameters such that the presence and degree of coronary artery disease may be detected.

2. The system of claim 1 further comprising:

d) a speaker coupled to said computer, said speaker being designed to provide an acoustical indication of the presence and degree of coronary artery disease by reproducing sounds from signals generated from said computer indicative of coronary artery disease.

3. The system of claim 1 further comprising:

d) a visual indicator coupled to said computer, said visual indicator being designed and configured to provide a first signal operative to indicate the presence of coronary artery disease, and a second signal operative to indicate the absence of coronary artery disease.

4. The apparatus of claim 1 wherein said microphone of said system comprises a phonocardiogram microphone for detecting cardiac acoustical activity consisting of a plurality of heart beats.

5. A method of detecting coronary artery disease in a human subject comprising the steps of:

a) detecting an acoustical signal generated from a heartbeat of said subject and converting said acoustical signal into an electrical signal;

b) processing said electrical signal generated in step a) to identify a first heart sound corresponding to the closure of the atrioventricular valves and the contraction of the ventricles, and a second heart sound corresponding to the closure of the aortic and pulmonary valves during said heartbeat, and the interval between said first and second heart sound;

c) determining the heart rate of said individual;

d) comparing the heart rate interval and the interval between said second and first heart sounds and estimating the sound energy level emanating from the coronary artery during said interval between said second and first heart sounds; and

e) comparing said energy level determined in step d) to a baseline energy level and identifying whether said energy level determined in step d) is indicative of coronary artery disease.

6. The method of claim 5 wherein in step e), the determination as to whether the human is afflicted with coronary artery disease is indicated by acoustically modifying the diastolic heart sounds between said second and first heart sounds, and presenting said sounds to a human operator via a speaker.

7. The method of claim 5 wherein in step e), the determination as to whether the human is afflicted with coronary artery disease is indicated by providing a visual signal.