Passive/non-invasive systemic and pulmonary blood pressure measurement

• US 6,050,950 A
• Filed: 12/18/1996
• Issued: 04/18/2000
• Est. Priority Date: 12/18/1996
• Status: Expired due to Term

• Current Assignee: AusculSciences, Inc.
• Original Assignee: Aurora Holdings, LLC
• Inventors: Mohler, Sailor
• Primary Examiner(s): Nasser, Robert L.
• Application Number:
  US08/769,156
• Time in Patent Office: 1,217 Days
• Field of Search: 600/485, 600/490, 600/493-6, 600/728, 600/586
• US Class Current: 600/485
• CPC Class Codes: A61B 5/0205 Simultaneously evaluating both cardiovascular conditions and different types of body conditions, e.g. heart and respiratory condition
• CPC Class Codes: A61B 7/00 Instruments for auscultation
• CPC Class Codes: A61B 7/04 Electric stethoscopes microphones, acoustic transducers therefor H04R

Abstract

An apparatus, operation and method for measurement of systemic and/or pulmonic blood pressure. The present invention offers a passive non-invasive method and system that can be used where measurement of systemic pressure with a traditional blood pressure cuff is contraindicated. The present invention also affords a means for early diagnosis and opportunity for intervention in patients with no symptoms or signs of elevated pulmonary blood pressure that can be performed as part of a routine physical exam. The present invention accomplishes this non-invasive measurement through detection, identification and characterization of the second heart sound acoustic signature associated with heart valve closure. An apparatus for measuring systemic and/or pulmonic blood pressure in accordance with the present invention includes a sensor assembly comprising a housing, an electronic module, a shock dampener, a mounting means, a transducer, an acoustic coupling and a back cover. The sensor assembly is connected to a data acquisition module which in turn is connected to a signal processing means, a remote connection means and a monitor. An improved acoustic coupling is disclosed that provides low-loss acoustic transmission coupling between the skin of the patient and the detector.

Claims

1. An apparatus for monitoring blood pressure comprising:

a means for detecting audio signals, where the audio signals are physiological sounds selected from the group consisting of aortic semilunar valve closure, pulmonary semilunar valve closure, and both aortic semilunar valve closure and pulmonary semilunar valve closure;

a means for processing the audio signals, connected to the audio signal detecting means and resulting in processed audio signals;

a means for processed audio signal storage, connected to the audio signal processing means;

a means for monitoring the processed audio signals, connected to the signal processing means; and

a means for determining blood pressure based upon the monitored processed audio signals.

2. An apparatus for monitoring blood pressure as claimed in claim 1, wherein the audio signal detecting means is a sensor assembly.

3. An apparatus for monitoring blood pressure as claimed in claim 2, wherein the sensor assembly comprises:

a housing having a front and a back;

an electronic module connected to the housing;

a shock dampener connected to the front of the housing;

a means for mounting connected to the housing;

a transducer connected to the mounting means;

an acoustic coupling connected to the transducer; and

a cover connected to the back of the housing.

4. An apparatus for monitoring blood pressure as claimed in claim 3, wherein the housing further comprises a sound deadening material.

5. An apparatus for monitoring blood pressure as claimed in claim 4, wherein the housing further comprises nickel plated aluminum.

6. An apparatus for monitoring blood pressure as claimed in claim 3, wherein the housing further comprises:

a rim having an inside and an outside, located on the periphery of the front of the housing;

a first indentation having an inside and an outside, that runs parallel and adjacent to the inside of the rim;

a second indentation that runs parallel and adjacent to the inside of the first indentation; and

a bore that is approximately centrally located within the second indentation.

7. An apparatus for monitoring blood pressure as claimed in claim 6, wherein the electronic module nests within the bore.

8. An apparatus for monitoring blood pressure as claimed in claim 3, wherein the shock dampener is an "O" ring.

9. An apparatus for monitoring blood pressure as claimed in claim 3, wherein the mounting means is a plastic mounting ring.

10. An apparatus for monitoring blood pressure as claimed in claim 3, wherein the transducer is a piezoelement.

11. An apparatus for monitoring blood pressure as claimed in claim 3, wherein the acoustic coupling is a parametric acoustic transconductor.

12. An apparatus for monitoring blood pressure as claimed in claim 11, wherein the parametric acoustic transconductor comprises latex foam.

13. An apparatus for monitoring blood pressure as claimed in claim 1, wherein the audio signal detecting means is a plurality of sensor assemblies.

14. An apparatus for monitoring blood pressure as claimed in claim 1, wherein the signal processing means is a computer with a central processing unit.

15. An apparatus for monitoring blood pressure as claimed in claim 14, wherein the computer with a central processing unit is an IBM compatible personal computer.

16. An apparatus for monitoring blood pressure as claimed in claim 1, wherein the means for signal storage further comprises an array of disks.

17. An apparatus for monitoring blood pressure as claimed in claim 1, wherein the means for signal storage further comprises an internal hard disk drive.

18. An apparatus for monitoring blood pressure as claimed in claim 1, wherein the means for signal storage further comprises an internal hard disk drive.

19. An apparatus for monitoring blood pressure as claimed in claim 1, further comprising:

a means for hard copy reproduction connected to the signal processing means.

20. An apparatus for monitoring blood pressure as claimed in claim 19, wherein the means for hard copy reproduction further comprises a printer.

21. An apparatus for monitoring blood pressure as claimed in claim 1, further comprising:

a means for remote connection connected to the signal processing means.

22. An apparatus for monitoring blood pressure as claimed in claim 21, wherein the means for remote connection further comprises a modem.

23. An apparatus for monitoring blood pressure as claimed in claim 1, wherein the means for monitoring further comprises a high resolution EGA color display monitor.

24. An apparatus for monitoring blood pressure as claimed in claim 1, wherein the means for monitoring further comprises a high resolution VGA color display monitor.

25. An apparatus for monitoring blood pressure as claimed in claim 1, further comprising:

a means for data acquisition connected to the signal detection means and the signal processing means.

26. An apparatus for monitoring blood pressure as claimed in claim 25, wherein the means for data acquisition comprises an amplifier.

27. An apparatus for monitoring blood pressure as claimed in claim 26, wherein the amplifier comprises a tailored bandpass amplifier.

28. An apparatus for monitoring blood pressure as claimed in claim 27, wherein the tailored bandpass amplifier comprises a low frequency response from a predetermined first point to a predetermined second point, and a higher frequency response of a predetermined level, from the predetermined second point to a predetermined third point.

29. An apparatus for monitoring blood pressure as claimed in claim 28, wherein the predetermined level is about 20 dB.

30. An apparatus for monitoring blood pressure as claimed in claim 28, wherein the predetermined first point is about 100 Hz, the predetermined second point is about 100 Hz and the predetermined third point is about 600 Hz.

31. An apparatus for monitoring blood pressure as claimed in claim 28, where in the predetermined second point is about 60 Hz.

32. An apparatus for determining a physiological condition comprising:

an acoustic coupling;

a transducer connected to the acoustic coupling, where the acoustic coupling is adapted to provide coupling between the skin of a patient and the transducer and where the transducer converts detected physiological sounds selected from the group consisting of aortic semilunar valve closure, pulmonary semilunar valve closure, and both aortic semilunar valve closure and pulmonary semilunar valve closure sounds into electronic signals;

an electronic modules connected to the transducer, where the electronic module detects and processes the electronic signals;

a data cable connected to the electronic module, where the data cable couples the electronic module with a data acquisition module, and where the data acquisition module performs at least one operation upon the electronic signals selected from the group of operations consisting of signal filtering, impedance matching, amplification and buffering to create modified electronic signals; and

a physiologic condition determining means connected to the acquisition module for determining said physiological condition.

33. An apparatus for determining a physiological condition as claimed in claim 32, wherein the data cable is a twisted shielded pair.