Brain function scan system

• US 6,052,619 A
• Filed: 08/07/1997
• Issued: 04/18/2000
• Est. Priority Date: 08/07/1997
• Status: Expired due to Term

• Current Assignee: New York University
• Original Assignee: New York University
• Inventors: John, Erwin Roy
• Primary Examiner(s): Nasser, Robert L.
• Application Number:
  US08/908,456
• Time in Patent Office: 985 Days
• Field of Search: 600/544, 600/545
• US Class Current: 600/544
• CPC Class Codes: A61B 5/0006 ECG or EEG signals
• CPC Class Codes: A61B 5/369 Electroencephalography [EEG] devices for psychotechnics A61B5/16
• CPC Class Codes: A61B 5/377 using evoked responses
• CPC Class Codes: A61B 5/4076 Diagnosing or monitoring particular conditions of the nervous system A61B5/4821, A61B5/4824 take precedence
• CPC Class Codes: A61B 5/7257 using Fourier transforms

Abstract

A portable EEG (electroencephalograph) instrument, especially for use in emergencies and brain assessments in physicians'"'"' offices, detects and amplifies brain waves and converts them into digital data for analysis by comparison with data from normal groups. In one embodiment, the EEG electrodes are in a headband which broadcasts the data, by radio or cellular phone, to a local receiver for re-transmission and/or analysis. In another embodiment, the subject is stimulated in two modes, i.e., aural and sensory, at two different frequencies to provide the subject'"'"'s EPs (Evoked Potentials), assessing transmission through the brainstem and thalamus.

Claims

1. A medical system to transmit data regarding brain injury or dysfunction comprising:

(a) a headband and at least two EEG (electroencephalograph) electrode means carried therein to detect a human subject'"'"'s brain waves, the electrode means being located as homologous pairs with one electrode means of each pair on the left and the other electrode of the pair on the right side of the brain;

(b) amplification means to amplify and digitize the detected brain waves and to produce subject brain wave data therefrom;

(c) switching means to switch the amplification means, in sequence, to different homologous (L/R) pairs of the electrode means in order to construct a scan;

(d) means to confirm stationarity of a subject'"'"'s brain state at a selected fiducial electrode across the set of N scans required to assess the brain state of the subject;

(e) means to extract measures from the group of absolute power, relative power, coherence (synchrony) and symmetry for each sample of EEG from a pair of electrodes and to average each of selected measures across the full set of scans;

(f) computer means to compare subject'"'"'s brain wave data of (e) with brain wave data based upon a normal group of subjects and to produce an almost real-time report based thereon regarding an excess or deficit of energy selected from the group of beta, alpha, theta or delta bands and to assess across sequential scans an increasing shift in local slow wave reflecting injury or dysfunction or, in each pair, asymmetric slow waves indicating cerebral ischemia.

2. A medical system as in claim 1 and print means to print a statistical probability map with interpolated values, using a color-coded heat scale with lines from red to yellow indicating significance of excesses and blue to white indicating deficits relative to the appropriate norm.

3. A medical system as in claim 2 and including means to validate the digitized brain waves by comparing odd and even split-half segments of data from the same electrode and under the same stimulus and about the same time and rejecting segments that do not satisfy a criterion of stationarity.

4. A medical system as in claim 1 and including means to validate the digitized brain waves by comparing odd and even split-half segments of data from the same electrode and under the same stimulus and about the same time and rejecting segments that do not satisfy criteria of stationarity.

5. A medical system as in claim 1 and display means to construct and display a color-coded topographic map displaying the statistical probability of the values of (f).

6. A medical system as in claim 1 and including computer means to combine the averaged data from all pairs of electrodes into one "virtual simultaneous" recording.

7. A medical system as in claim 1, and stimulus means to apply concurrent stimulation to the subject in different modes, e.g., auditory clicks and electric pulses to the skin, the concurrent stimuli being at two or more different frequencies.