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Apparatus for multi-well microscale synthesis

  • US 6,054,100 A
  • Filed: 11/18/1997
  • Issued: 04/25/2000
  • Est. Priority Date: 11/18/1996
  • Status: Expired due to Fees
First Claim
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1. An apparatus for multiple, simultaneous synthesis, comprising:

  • a synthesis block, said synthesis block including a plurality of reaction wells integrally formed within said block and arranged in ordered array, each well having an inlet portion and an outlet spout, said synthesis block further having a periphery;

    a first sheet gasket sealable upon the inlet portions;

    a second sheet gasket sealable upon the outlet spouts;

    an upper cover for pressured engagement with said first sheet gasket;

    a lower cover for pressured engagement with said second sheet gasket;

    attachment means for releasably and independently attaching each one of said upper and lower covers to said periphery, said attachment means including said synthesis block having at least one protruding structure located on the periphery for attachment of said upper and lower covers; and

    said attachment means further includes a reinforcement assembly having an upper collar and a lower collar for opposable sandwiching of the at least one protruding structure, each of said upper and lower covers attached to one of said upper and lower collars.

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