Xylitol delivery

• US 6,054,143 A
• Filed: 12/23/1998
• Issued: 04/25/2000
• Est. Priority Date: 03/24/1998
• Status: Expired due to Term

• Current Assignee: Xlear
• Original Assignee: Alonzo H. Jones
• Inventors: Jones, Alonzo H.
• Primary Examiner(s): Cook, Rebecca
• Application Number:
  US09/220,283
• Time in Patent Office: 489 Days
• Field of Search: 514/23, 514/738, 424/434
• US Class Current: 424/434
• CPC Class Codes: A61K 31/047 having two or more hydroxy groups, e.g. sorbitol
• CPC Class Codes: A61K 31/7004 Monosaccharides having only carbon, hydrogen and oxygen atoms
• CPC Class Codes: A61K 9/0043 Nose
• CPC Class Codes: A61P 11/02 Nasal agents, e.g. decongestants
• CPC Class Codes: A61P 11/06 Antiasthmatics
• CPC Class Codes: A61P 27/16 Otologicals
• CPC Class Codes: A61P 29/00 Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
• CPC Class Codes: A61P 31/04 Antibacterial agents

Abstract

Nasopharyngeal congestion, irritation, and inflammation and associated upper respiratory infections such as otitis media, sinusitis are adjunctivly treated and prevented by nasal application of xylitol/xylose in a saline solution.

Claims

1. A method of cleaning the nasopharynx in a human in need of said method which comprises nasally administering an effective amount of xylitol/xylose in solution.

2. The method as defined in claim 1 wherein the solution is administered as a spray.

3. The method as defined in claim 2 further comprising:

wherein two sprays of said xylitol/xylose in solution is administered to an infant about seven times a day.

4. The method as defined in claim 2 further comprising:

said human is an infant and two sprays are administered at each diaper change.

5. The method as defined in claim 1 wherein the solution is administered by drops.

6. The method as defined in claim 1 wherein the solution is administered by a swab.

7. The method as defined in claim 1 wherein said xylitol/xylose in aqueous solution comprises from one gram to 64 grams of xylitol/xylose in 100 cc of solution.

8. The method as defined in claim 7 wherein said solution is a hypotonic saline solution which has a range from 0.45% to 0.85% sodium chloride.

9. The method as defined in claim 1 wherein said xylitol/xylose in saline solution consists of 5 grams xylitol/xylose in 45 cubic centimeters of water having 0.65% sodium chloride and effective amounts of benzalkonium chloride and phenylcarbinol.

10. The method as defined in claim 9 further comprising:

wherein two sprays of said xylitol/xylose in saline solution is administered to an infant about seven times a day.

11. The method as defined in claim 9 further comprising:

said human is an infant and the spray is administered at each diaper change.

12. The method as defined in claim 8 wherein said solution is administered by swab.