Ophthalmic solutions viscosified with tamarind seed polysaccharide
First Claim
1. A method for treating dry eye syndrome, comprising topically administering to an eye of an animal in need thereof a viscosified ophthalmic solution comprising an effective amount of a polysaccharide fraction of tamarind gum.
3 Assignments
0 Petitions
Accused Products
Abstract
The polysaccharide fraction of tamarind gum, a product of natural origin obtained from the seeds of Tamarindus indica, is used for the production of a thickened ophthalmic solution having a pseudoplastic rheological behaviour and mucoadhesive properties. Said solution is useful as artificial tear and as vehicle for sustained release ophthalmic drugs. The concentrations of tamarind seed polysaccharide preferably employed in ophthalmic preparations for use as artificial tears, i.e. as products for replacing and stabilising the natural tear fluid, particularly indicated for the treatment of dry eye syndrome, are comprised between 0.7 and 1.5% by weight. The concentrations of tamarind seed polysaccharide preferably employed in the production of vehicles (i.e. delivery systems) for ophthalmic drugs, having the function of prolonging the permanence time of said medicaments at their site of action, are comprised between 1 and 4% by weight.
69 Citations
27 Claims
- 1. A method for treating dry eye syndrome, comprising topically administering to an eye of an animal in need thereof a viscosified ophthalmic solution comprising an effective amount of a polysaccharide fraction of tamarind gum.
- 6. A method of delivering a topical ophthalmic drug to the eye, comprising topically administering to an eye of an animal in need thereof a composition comprising an effective amount of said drug and a polysaccharide fraction of tamarind gum.
- 13. A method of delivering one or more topical ophthalmic drugs to the eye, comprising topically administering to an eye of an animal in need thereof a composition comprising an effective amount of one or more of said drugs and a polysaccharide fraction of tamarind gum.
-
17. An ophthalmic formulation, comprising:
-
an effective amount of a purified polysacharide fraction of tamarind gum, and an ophthalmologically acceptable solution. - View Dependent Claims (18, 19, 20)
-
-
21. A sustained release topical ophthalmic formulation, comprising:
-
an effective amount of one or more pharmaceutically active ingredients, and an effective amount of a purified polysaccharide fraction of tamarind gum. - View Dependent Claims (22, 23)
-
-
24. An artificial tear formulation, comprising:
-
an effective amount of a purified polysaccharide fraction of tamarind gum, and an ophthalmologically acceptable solution. - View Dependent Claims (25, 26, 27)
-
Specification