Molecular receptors in metal oxide sol-gel materials prepared via molecular imprinting
First Claim
1. A method for molecularly imprinting the surface of a sol-gel material, comprising:
- forming a solution comprised of a sol-gel material, a solvent, an imprinting molecule, and a functionalizing siloxane monomer of the form Si(OR)3-n R'"'"'Xn, wherein n is an integer between zero and three, R is hydrogen or an alkane of carbon length less than five, R'"'"' is a spacer molecular group comprising a carbon-containing segment of a length not exceeding 15 Å
, and X is a functional group capable of reacting with the imprinting molecule;
evaporating the solvent; and
removing the imprinting molecule to form the molecularly imprinted metal oxide sol-gel material.
3 Assignments
0 Petitions
Accused Products
Abstract
A method is provided for molecularly imprinting the surface of a sol-gel material, by forming a solution comprised of a sol-gel material, a solvent, an imprinting molecule, and a functionalizing siloxane monomer of the form Si(OR)3-n Xn, wherein n is an integer between zero and three and X is a functional group capable of reacting with the imprinting molecule, evaporating the solvent, and removing the imprinting molecule to form the molecularly imprinted metal oxide sol-gel material. The use of metal oxide sol-gels allows the material porosity, pore size, density, surface area, hardness, electrostatic charge, polarity, optical density, and surface hydrophobicity to be tailored and be employed as sensors and in catalytic and separations operations.
243 Citations
26 Claims
-
1. A method for molecularly imprinting the surface of a sol-gel material, comprising:
-
forming a solution comprised of a sol-gel material, a solvent, an imprinting molecule, and a functionalizing siloxane monomer of the form Si(OR)3-n R'"'"'Xn, wherein n is an integer between zero and three, R is hydrogen or an alkane of carbon length less than five, R'"'"' is a spacer molecular group comprising a carbon-containing segment of a length not exceeding 15 Å
, and X is a functional group capable of reacting with the imprinting molecule;evaporating the solvent; and removing the imprinting molecule to form the molecularly imprinted metal oxide sol-gel material. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16)
-
-
17. A method for molecularly imprinting the surface of a sol-gel material, comprising:
-
forming a solution comprised of a sol-gel material, a solvent, an imprinting molecule, and the functionalizing siloxane monomer 3-trimethoxysilyl propyl-1-guanidinium chloride, wherein the imprinting molecule is a compound selected from the group consisting essentially of phosphonic acids, phosphoric acids, sulfonic acids, sulfuric acids, and carboxylic acids; evaporating the solvent; and removing the imprinting molecule to form the molecularly imprinted metal oxide sol-gel material. - View Dependent Claims (18, 19, 20)
-
- 21. A molecularly imprinted metal oxide sol-gel material comprising 3-trimethoxysilyl propyl-1-guanidinium chloride attached to a metal oxide sol gel, wherein the metal oxide sol-gel material has been molecularly imprinted with an imprinting molecule selected from the group consisting essentially of phosphonic acids, phosphoric acids, sulfonic acids, sulfuric acids, and carboxylic acids.
Specification