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Methods and compositions for the modulation of cell proliferation and wound healing

  • US 6,063,396 A
  • Filed: 02/12/1996
  • Issued: 05/16/2000
  • Est. Priority Date: 10/26/1994
  • Status: Expired due to Fees
First Claim
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1. An implant comprising:

  • at least one agent which modulates proliferation of target cells, wherein said agent is bound to a polymer via a reactive group which mediates an interaction selected from the group consisting of;

    a hydrophobic interaction, a hydrophilic interaction, and a covalent interaction, wherein said interaction is labile under physiological conditions, so that said agent is released from said polymer when contacted with a tissue comprising said target cells without the use of an exogenously supplied releasing agent which changes the physiological conditions in said tissue.

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