Device and method for detecting leakage of filter film

• US 6,065,329 A
• Filed: 06/24/1999
• Issued: 05/23/2000
• Est. Priority Date: 12/27/1996
• Status: Expired due to Term

• Current Assignee: Asahi Kasei Medical Co., Ltd. (Asahi Kasei Corporation)
• Original Assignee: Asahi Kasei Kogyo Kabushiki Kaisha
• Inventors: Itose, Takao, Fukada, Seiji
• Primary Examiner(s): Larkin, Daniel S.
• Application Number:
  US09/331,768
• Time in Patent Office: 334 Days
• Field of Search: 73/37, 73/40
• US Class Current: 73/40
• CPC Class Codes: B01D 65/102 Detection of leaks in membranes
• CPC Class Codes: G01N 15/0826 and measuring fluid flow rate, i.e. permeation rate or pressure change
• CPC Class Codes: G01N 2015/084 Testing filters

Abstract

An apparatus for detecting leakage through a filtration membrane which comprises a gas-supplying source for supplying a gas to one of two spaces formed by partition with the filtration membrane, a gas-detecting device for measuring the degree of leakage of the gas into the other space, and further preventing the undesirable influence of the supplied gas on the gas-detecting device.

Claims

1. An apparatus for detecting leakage through a filtration membrane which comprises a gas-supplying means for supplying a gas to one of two spaces formed by partition with the filtration membrane, a gas-detecting means for measuring the degree of leakage of the gas into the other space, and a means for preventing the undesirable influence of the supplied gas on said gas-detecting means.

2. An apparatus according to claim 1, wherein said gas-detecting means is a pressure-detecting means for measuring the degree of leakage of the gas in terms of a pressure change.

3. An apparatus according to claim 2, wherein the means for preventing the undesirable influence of the supplied gas on said gas-detecting means is a three-way valve.

4. An apparatus according to claim 2 or 3, wherein said pressure-detecting means is a micro-differential pressure gauge.

5. A method for detecting leakage through a filtration membrane which comprises pressurizing with a gas one of two spaces formed by partition with the filtration membrane to a pressure at which said gas does not flow out through normal pores, filling the other space with an examining liquid, determining the flow rate of gas leaking out through pinholes of the filtration membrane, and thereby investigating the presence of the pinholes of the filtration membrane, wherein the flow rate of the leaking gas is measured after first excluding the influence of the expansion of the filtration membrane by the pressurization.

6. A method according to claim 5, wherein the filtration membrane is a virus-separating membrane.

7. A method according to claim 6, wherein the virus-separating membrane is a membrane made of regenerated cellulose.