Dietary supplement for supporting cerebrovascular tone and treating migraine headaches

• US 6,068,999 A
• Filed: 06/25/1998
• Issued: 05/30/2000
• Est. Priority Date: 06/25/1998
• Status: Expired due to Term

• Current Assignee: Akeso Health Sciences, LLC, IntraMedical Imaging, LLC, Levin & Hemes, Natural Science Corporation
• Original Assignee: Natural Science Corporation
• Inventors: Hendrix, Curt
• Primary Examiner(s): Lilling, Herbert J.
• Application Number:
  US09/104,862
• Time in Patent Office: 705 Days
• Field of Search: 424/195.1, 514/468
• US Class Current: 424/764
• CPC Class Codes: A61K 2300/00 Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
• CPC Class Codes: A61K 36/28 Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
• CPC Class Codes: A61P 25/06 Antimigraine agents
• CPC Class Codes: A61P 9/00 Drugs for disorders of the cardiovascular system

Abstract

The present invention relates to a dietary supplement for the support of normal cerebrovascular tone. Extracts of the feverfew plant in combination with magnesium and riboflavin, either singly or in combination provide the major therapeutic enhancement in the reduction of migraine headaches and the associated symptoms.

Claims

1. A dietary supplement comprising

an extract from the feverfew plant,

magnesium, and

riboflavin,

wherein the feverfew extract contains about 0.7% parthenolide and the magnesium is provided as a combination of magnesium oxide and magnesium citrate.

3. The dietary supplement as set forth in claim 1, wherein said feverfew extract is present in an amount of about 50 milligrams per unit dose, said magnesium is present in an amount of about 150 milligrams per unit dose, and said riboflavin is present in an amount of about 200 milligrams per unit dose.

5. The dietary supplement as set forth in claim 3, wherein said magnesium further comprises a one to one ratio of magnesium citrate and magnesium oxide.

7. The dietary supplement of claim 3, wherein a daily dosage is at least two unit doses.

2. A dietary supplement comprising

an extract from the feverfew plant, and magnesium wherein the feverfew extract contains about 0.7% parthenolide and the magnesium is provided as a combination of magnesium oxide and magnesium citrate.

4. The dietary supplement as set forth in claim 2, wherein said feverfew extract is present in an amount of about 50 milligrams per unit dose, and said magnesium is present in an amount of about 150 milligrams per unit dose.

6. A dietary supplement as set forth in claim 4, wherein said magnesium further comprises a one to one ratio of magnesium citrate and magnesium oxide.

8. The dietary supplement of claim 4, wherein a daily dosage is at least two unit doses.

9. A method for reducing the symptoms of migraine headaches comprising administering a therapeutically effective amount of a dietary supplement comprising:

an extract of the feverfew plant

riboflavin and

magnesium

wherein the extract from the feverfew plant contains about 0.7% parthenolide and the magnesium is provided as a combination of magnesium oxide and magnesium citrate.

10. The method for reducing the symptoms of migraine headaches as set forth in claim 9, wherein said therapeutically effective dose is a daily dosage of feverfew extract of about 100 milligrams, of riboflavin of about 400 milligrams, and of magnesium of about 300 milligrams.

11. The method of claim 9, wherein the magnesium oxide and the magnesium citrate are present in a ratio of about one to one.

12. A method of reducing the symptoms of migraine headaches comprising administering a therapeutically effective amount of a dietary supplement comprising:

an extract of feverfew plant, and

magnesium

wherein the extract of feverfew plant contains about 0.7% parthenolide and the magnesium is provided as a combination magnesium oxide and magnesium citrate.

14. The method of claim 12 wherein the magnesium oxide and the magnesium citrate are present in a ratio of about one to one.

13. A method of reducing the symptoms of migraine headaches comprising the steps of administering a therapeutically effective amount of a dietary supplement comprising:

an extract of feverfew plant, and

magnesium wherein the magnesium is provided as a combination magnesium oxide and a magnesium salt of an organic acid.