Multiple channel, sequential, cardiac pacing systems
First Claim
1. A pacing system for improving the hemodynamic efficiency of a sick heart suffering from conduction delays in conducting spontaneous or evoked depolarizations originating in one of the right or left atrium to the other of the left or right atrium comprising:
- right atrial lead means for locating first and second right atrial pace/sense electrodes in relation with the right atrium;
left atrial lead means for locating first and second left atrial pace/sense electrodes in relation with the left atrium;
right atrial depolarization sensing means coupled with said right atrial lead means for sensing spontaneous cardiac depolarizations originating in the right atrium and conducted cardiac depolarizations originating in the left atrial from a spontaneous cardiac depolarization or delivery of a left atrial pacing pulse to the left atrium and for providing a right atrial sensed event signal in response to either a sensed spontaneous or conducted cardiac depolarization;
left atrial depolarization sensing means coupled with said left atrial lead means for sensing spontaneous cardiac depolarizations originating in the left atrium and conducted cardiac depolarizations originating in the right atrial from a spontaneous cardiac depolarization or delivery of a right atrial pacing pulse to the right atrium and for providing a left atrial sensed event signal in response to either a sensed spontaneous or conducted cardiac depolarization;
escape interval timing means for timing an escape interval establishing a pacing rate and providing an escape interval pace trigger signal at the time out of the escape interval, the escape interval timing means further comprising reset means for restarting the timing of the escape interval in response to one of the right or left atrial sensed event signals;
right atrial pacing pulse output means coupled with said right atrial lead means and selectively responsive to an applied pace trigger signal for generating and delivering a right atrial pacing pulse to said right atrial lead means to evoke a right atrial depolarization;
left atrial pacing pulse output means coupled with said left atrial lead means and selectively responsive to an applied pace trigger signal for generating and delivering a left atrial pacing pulse to said left atrial lead means to evoke a left atrial depolarization;
means for applying said escape interval pace trigger signal to one of said right atrial pacing pulse output means or said left atrial pacing pulse output means;
left atrial conduction delay window timing means coupled with said escape interval timing means and said right atrial depolarization sensing means for timing a left atrial conduction delay window from a right atrial sensed event signal and selectively from an escape interval pace trigger signal and for providing a left atrial pace trigger signal at the expiration of the left atrial conduction delay window time, said left atrial conduction delay window timing means further coupled with said left atrial depolarization sensing means and comprising left atrial window terminating means for terminating the timing out of the left atrial conduction delay window in response to a left atrial sensed event signal;
means for applying said left atrial pace trigger signal to said left atrial pacing pulse output means as a pace trigger signal for triggering the generation and delivery of a left atrial pacing pulse to said left atrial lead means;
right atrial conduction delay window timing means coupled with said escape interval timing means and said left atrial depolarization sensing means for timing a right atrial conduction delay window from a left atrial sensed event signal and selectively from an escape interval pace trigger signal and for providing a right atrial pace trigger signal at the expiration of the right atrial conduction delay window time, said right atrial conduction delay window timing means further coupled with said right atrial depolarization sensing means and comprising right atrial window terminating means for terminating the timing out of the right atrial conduction delay window in response to a right atrial sensed event signal; and
means for applying said right atrial pace trigger signal to said right atrial pacing pulse output means as a pace trigger signal for triggering the generation and delivery of a right atrial pacing pulse to said right atrial lead means;
whereby an excessive conduction delay between a spontaneous or evoked depolarization in the right atrium and the conducted depolarization wave in the left atrial or an excessive conduction delay between a spontaneous or evoked depolarization in the left atrium and the conducted depolarization wave in the right atrium is corrected by generation and delivery of a pacing pulse to the left or right atrium, respectively at the timing out of the corresponding conduction delay window.
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Abstract
Multi-chamber cardiac pacing systems for providing synchronous pacing to at least the two upper heart chambers or the two lower heart chambers or to three heart chambers or to all four heart chambers employing programmable conduction delay window (CDW) times timed out from paced and sensed events occurring in each heart chamber are disclosed. The synchronous pacing of one of the right and left heart chambers is provided on demand following expiration of programmable pace and sense CDWs that are started by both a paced event and a sensed event first occurring in the other of the right and left heart chambers. The delivery of the pacing pulse is inhibited by a sensed event detected in the other of the right and left heart chambers before the expiration of the corresponding CDW. In a four channel atrial and ventricular pacing system, the right and left atrial chambers are sensed and paced as necessary upon at the end of a V-A escape interval and right and left AV delays are commenced for sensing ventricular depolarizations in the right and left ventricles. The four channel system is programmable to pace and sense in three selected heart chambers.
234 Citations
18 Claims
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1. A pacing system for improving the hemodynamic efficiency of a sick heart suffering from conduction delays in conducting spontaneous or evoked depolarizations originating in one of the right or left atrium to the other of the left or right atrium comprising:
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right atrial lead means for locating first and second right atrial pace/sense electrodes in relation with the right atrium; left atrial lead means for locating first and second left atrial pace/sense electrodes in relation with the left atrium; right atrial depolarization sensing means coupled with said right atrial lead means for sensing spontaneous cardiac depolarizations originating in the right atrium and conducted cardiac depolarizations originating in the left atrial from a spontaneous cardiac depolarization or delivery of a left atrial pacing pulse to the left atrium and for providing a right atrial sensed event signal in response to either a sensed spontaneous or conducted cardiac depolarization; left atrial depolarization sensing means coupled with said left atrial lead means for sensing spontaneous cardiac depolarizations originating in the left atrium and conducted cardiac depolarizations originating in the right atrial from a spontaneous cardiac depolarization or delivery of a right atrial pacing pulse to the right atrium and for providing a left atrial sensed event signal in response to either a sensed spontaneous or conducted cardiac depolarization; escape interval timing means for timing an escape interval establishing a pacing rate and providing an escape interval pace trigger signal at the time out of the escape interval, the escape interval timing means further comprising reset means for restarting the timing of the escape interval in response to one of the right or left atrial sensed event signals; right atrial pacing pulse output means coupled with said right atrial lead means and selectively responsive to an applied pace trigger signal for generating and delivering a right atrial pacing pulse to said right atrial lead means to evoke a right atrial depolarization; left atrial pacing pulse output means coupled with said left atrial lead means and selectively responsive to an applied pace trigger signal for generating and delivering a left atrial pacing pulse to said left atrial lead means to evoke a left atrial depolarization; means for applying said escape interval pace trigger signal to one of said right atrial pacing pulse output means or said left atrial pacing pulse output means; left atrial conduction delay window timing means coupled with said escape interval timing means and said right atrial depolarization sensing means for timing a left atrial conduction delay window from a right atrial sensed event signal and selectively from an escape interval pace trigger signal and for providing a left atrial pace trigger signal at the expiration of the left atrial conduction delay window time, said left atrial conduction delay window timing means further coupled with said left atrial depolarization sensing means and comprising left atrial window terminating means for terminating the timing out of the left atrial conduction delay window in response to a left atrial sensed event signal; means for applying said left atrial pace trigger signal to said left atrial pacing pulse output means as a pace trigger signal for triggering the generation and delivery of a left atrial pacing pulse to said left atrial lead means; right atrial conduction delay window timing means coupled with said escape interval timing means and said left atrial depolarization sensing means for timing a right atrial conduction delay window from a left atrial sensed event signal and selectively from an escape interval pace trigger signal and for providing a right atrial pace trigger signal at the expiration of the right atrial conduction delay window time, said right atrial conduction delay window timing means further coupled with said right atrial depolarization sensing means and comprising right atrial window terminating means for terminating the timing out of the right atrial conduction delay window in response to a right atrial sensed event signal; and means for applying said right atrial pace trigger signal to said right atrial pacing pulse output means as a pace trigger signal for triggering the generation and delivery of a right atrial pacing pulse to said right atrial lead means; whereby an excessive conduction delay between a spontaneous or evoked depolarization in the right atrium and the conducted depolarization wave in the left atrial or an excessive conduction delay between a spontaneous or evoked depolarization in the left atrium and the conducted depolarization wave in the right atrium is corrected by generation and delivery of a pacing pulse to the left or right atrium, respectively at the timing out of the corresponding conduction delay window. - View Dependent Claims (2, 3, 4, 5, 6)
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7. A pacing method for improving the hemodynamic efficiency of a sick heart suffering from conduction delays in conducting spontaneous or evoked depolarizations originating in one of the right or left atrium to the other of the left or right atrium comprising the steps of:
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locating first and second right atrial pace/sense electrode in relation with the right atrium; locating first and second left atrial pace/sense electrodes in relation with the left atrium; sensing spontaneous and evoked cardiac depolarizations in the right atrium across said right atrial pace/sense electrodes and providing a right atrial sensed event signal; sensing spontaneous and evoked cardiac depolarizations in the left atrium across said left atrial pace/sense electrodes and providing a left atrial sensed event signal; timing an escape interval establishing a pacing rate and providing an escape interval pace trigger signal at the time out of the escape interval; restarting the timing of the escape interval in response to one of the right or left atrial sensed event signals; in response to the escape interval pace trigger signal, selectively triggering either right atrial pacing pulse output means coupled with said right atrial pace/sense electrodes to generate and deliver a right atrial pacing pulse to said right atrial pace/sense electrodes to evoke a right atrial depolarization or left atrial pacing pulse output means coupled with said left atrial pace/sense electrodes to generate and deliver a left atrial pacing pulse to said left atrial lead means to evoke a left atrial depolarization; timing a left atrial conduction delay window from a right atrial sensed event signal or from generation of a right atrial pacing pulse and providing a left atrial pace trigger signal at the expiration of the left atrial conduction delay window terminating the timing out of the left atrial conduction delay window in response to a left atrial sensed event signal; applying said left atrial pace trigger signal to said left atrial pacing pulse output means to trigger the generation and delivery of a left atrial pacing pulse to said left atrial lead means; timing a right atrial conduction delay window from a left atrial sensed event signal or from generation of a left atrial pacing pulse and providing a right atrial pace trigger signal at the expiration of the right atrial conduction delay window terminating the timing out of the right atrial conduction delay window in response to a right atrial sensed event signal; and applying said right atrial pace trigger signal to said right atrial pacing pulse output means to trigger the generation and delivery of a right atrial pacing pulse to said right atrial lead means; whereby an excessive conduction delay between a spontaneous or evoked depolarization in one of the right or left atrium and the conducted depolarization wave in the other of the left or right atrium is corrected by generation and delivery of a pacing pulse at the timing out of the conduction delay window. - View Dependent Claims (8, 9, 10)
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11. A pacing method for improving the hemodynamic efficiency of a sick heart suffering from conduction delays in conducting spontaneous or evoked depolarizations originating in the right atrium to the left atrium comprising the steps of:
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locating first and second right atrial pace/sense electrode in relation with the right atrium; locating first and second left atrial pace/sense electrodes in relation with the left atrium; sensing spontaneous and evoked cardiac depolarizations in the right atrium across said right atrial pace/sense electrodes and providing a right atrial sensed event signal; sensing spontaneous and evoked cardiac depolarizations in the left atrium across said left atrial pace/sense electrodes and providing a left atrial sensed event signal; timing an escape interval establishing a pacing rate and providing an escape interval pace trigger signal at the time out of the escape interval; restarting the timing of the escape interval in response to the right atrial sensed event signals; in response to the escape interval pace trigger signal, triggering the right atrial pacing pulse output means coupled with said right atrial pace/sense electrodes to generate and deliver a right atrial pacing pulse to said right atrial pace/sense electrodes to evoke a right atrial depolarization; timing a left atrial conduction delay window from a right atrial sensed event signal or from generation of a right atrial pacing pulse and providing a left atrial pace trigger signal at the expiration of the left atrial conduction delay window terminating the timing out of the left atrial conduction delay window in response to a left atrial sensed event signal; and applying said left atrial pace trigger signal to said left atrial pacing pulse output means to trigger the generation and delivery of a left atrial pacing pulse to said left atrial lead means; whereby an excessive conduction delay between a spontaneous or evoked depolarization in the right atrium and the conducted depolarization wave in the left atrium is corrected by generation and delivery of a pacing pulse at the timing out of the conduction delay window. - View Dependent Claims (12, 13, 14)
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15. A pacing system for improving the hemodynamic efficiency of a sick heart suffering from conduction delays in conducting spontaneous or evoked depolarizations originating in the right atrium to the left atrium comprising:
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right atrial lead means for locating first and second right atrial pace/sense electrode in relation with the right atrium; left atrial lead means for locating first and second left atrial pace/sense electrodes in relation with the left atrium; right heart sensing means for sensing spontaneous and evoked cardiac depolarizations in the right atrium across said right atrial pace/sense electrodes and providing a right atrial sensed event signal; left heart sensing means for sensing spontaneous and evoked cardiac depolarizations in the left atrium across said left atrial pace/sense electrodes and providing a left atrial sensed event signal; escape interval timing means for timing an escape interval establishing a pacing rate and providing an escape interval pace trigger signal at the time out of the escape interval; reset means for restarting the timing of the escape interval in response to the right atrial sensed event signals; right atrial pacing pulse output means coupled with said right atrial pace/sense electrodes responsive to the escape interval pace trigger signal for generating and delivering a right atrial pacing pulse to said right atrial pace/sense electrodes to evoke a right atrial depolarization; means for timing a left atrial conduction delay window from a right atrial sensed event signal or from generation of a right atrial pacing pulse and providing a left atrial pace trigger signal at the expiration of the left atrial conduction delay window; means for terminating the timing out of the left atrial conduction delay window in response to a left atrial sensed event signal; and left atrial pacing pulse output means coupled with said left atrial pace/sense electrodes and responsive to said left atrial pace trigger signal for generating and delivering a left atrial pacing pulse to said left atrial lead means; whereby an excessive conduction delay between a spontaneous or evoked depolarization in the right atrium and the conducted depolarization wave in the left atrium is corrected by generation and delivery of a pacing pulse at the timing out of the conduction delay window. - View Dependent Claims (16, 17, 18)
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Specification