Analytical system and method
DCFirst Claim
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1. An analytical system comprising:
- a sample substrate having a plurality of mesoscale channels disposed therein, the plurality of channels connecting a plurality of reservoirs, each of the plurality of channels having at least one cross-sectional dimension between about 0.1 and 500 μ
m;
a base unit;
a sample substrate interface array disposed on an adapter that is removably attached to the base unit and comprising a sample substrate attachment region including a plurality of flow biasing connectors disposed thereon at least one of the flow biasing connectors comprises a pressure source, the flow biasing connectors being positioned within the substrate attachment region to mate with the plurality of reservoirs when the substrate is placed in the substrate attachment region; and
an energy emission detector disposed in the base unit and positioned to detect energy emitted from at least one of the channels disposed in the sample substrate, when the sample substrate is placed in the sample substrate attachment region.
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Abstract
An analytical or preparatory system comprised as a base unit, an adapter, and a substrate. The adapter is attached to an attachment region on the base unit, and the substrate is attached to an attachment region on the adapter. The adapter permits the base unit to be interfaced with a wide variety of different substrates to perform chemical and biological analytical analyses and preparatory procedures.
304 Citations
14 Claims
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1. An analytical system comprising:
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a sample substrate having a plurality of mesoscale channels disposed therein, the plurality of channels connecting a plurality of reservoirs, each of the plurality of channels having at least one cross-sectional dimension between about 0.1 and 500 μ
m;a base unit; a sample substrate interface array disposed on an adapter that is removably attached to the base unit and comprising a sample substrate attachment region including a plurality of flow biasing connectors disposed thereon at least one of the flow biasing connectors comprises a pressure source, the flow biasing connectors being positioned within the substrate attachment region to mate with the plurality of reservoirs when the substrate is placed in the substrate attachment region; and an energy emission detector disposed in the base unit and positioned to detect energy emitted from at least one of the channels disposed in the sample substrate, when the sample substrate is placed in the sample substrate attachment region. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14)
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Specification