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Stable protein-nickel particles and methods of production and use thereof

  • US 6,074,884 A
  • Filed: 10/09/1997
  • Issued: 06/13/2000
  • Est. Priority Date: 10/09/1997
  • Status: Expired due to Term
First Claim
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1. A stable protein-coated nickel particle useful in biological assays, consisting essentially of:

  • (a) a nickel particle having removed from the surface thereof by ultrasonification nickel oxide;

    (b) a linker attached to said nickel particle, said linker having a free amino group; and

    (e) a protein attached to said linker by covalently bonding to said free amino group.

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