Assembly containing an electrolytically severable joint for endovascular embolic devices

• US 6,077,260 A
• Filed: 02/19/1998
• Issued: 06/20/2000
• Est. Priority Date: 02/19/1998
• Status: Expired due to Term

• Current Assignee: Stryker European Operations Holdings, LLC (Stryker Corporation)
• Original Assignee: Target Therapeutics, Inc. (Boston Scientific Corporation)
• Inventors: Engelson, Erik T., Carrison, Harold F., Wheelock, E. Thomas
• Primary Examiner(s): COHEN, LEE S
• Application Number:
  US09/026,373
• Time in Patent Office: 852 Days
• Field of Search: 606/1, 606/32, 606/108, 606/191
• US Class Current: 606/32
• CPC Class Codes: A61B 17/12022 Occluding by internal devices, e.g. balloons or releasable wires plugging an opening in the wall of an organ A61B17/0057; occluders for the cervical canal A61F6/146; vas deferens occluders A61F6/20
• CPC Class Codes: A61B 17/1214 Coils or wires
• CPC Class Codes: A61B 2017/12063 electrolytically detachable

Abstract

This invention is an apparatus for the formation of occlusions in spaces in the human body, occluding such as thrombi in arteries, veins, aneurysms, vascular malformations and arteriovenous fistulas. In particular, it deals with a one piece assembly having an improved electrolytically erodable link to an occlusive member and further having an incorporated return electrode in the assembly. The occlusion-forming member is introduced to and is intended to remain at the desired occlusion site. The invention also relates to the joint itself. The invention further includes a method for introduction and electrolytic separation of the device.

Claims

1. A wire assembly for use in formation of an occlusion in a body cavity in the presence of ionic body fluids comprising:

a conductive implant detachably connected to a pusher wire, said pusher wire being insulated from said conductive implant, and

an electrolytically severable joint disposed between said implant and said pusher wire, said joint adapted for releasing said conductive implant from said pusher wire upon imposition of a current in said pusher wire, wherein said conductive implant forms a return path for current provided to said assembly through ionic body fluids.

2. The wire assembly of claim 1 wherein said implant comprises a coil.

3. The wire assembly of claim 2 wherein said coil comprises a platinum alloy coil.

4. The wire assembly of claim 1 wherein said electrolytically severable joint is tubular.

5. A wire assembly for use in formation of an occlusion in a body cavity comprising:

a composite core wire having a conductive member and a further conductive member in electrical contact with said conductive member,

an implant in electrical contact with said further conductive member, and

an electrolytically severable joint mechanically joining said composite core wire to said implant, electrically insulated from said conductive member and said further conductive member, said joint causing release of said implant and causing separation of said said conductive member from said further conductive member upon imposition of current to said joint, wherein said implant forms a return path for current provided to said conductive member through ionic body fluids.

6. The wire assembly of claim 5 wherein said implant comprises a coil.

7. The wire assembly of claim 6 wherein said coil comprises a platinum alloy coil.

8. The wire assembly of claim 5 wherein said electrolytically severable joint is tubular.

9. A wire assembly for use in formulation of an occlusion in a body cavity and suitable for delivery to said body cavity using a catheter comprising:

a composite core wire, said composite core wire having a longitudinal axis, a proximal end, a distal end, a first electrically conductive member and a second electrically conductive member, said first and second electrically conductive members being electrically insulated from each other and adapted to be electrically insulated from surrounding body fluids,

an implant, said implant having a longitudinal axis, a proximal end, a distal end and a third electrically conductive member, said third electrically conductive member being electrically insulated from said second electrically conductive member and having a proximal end and a distal end, said third electrically conductive member being configured to carry electrical current between the distal end of said first electrically conductive member and an exposed area of said implant, said exposed area adapted to have direct electrical contact with both the distal end of said third electrically conductive member and surrounding body fluids, and

an electrolytically erodable junction, said electrolytically erodable junction being configured to releasably attach the proximal end of said implant to the distal end of said composite core wire and to urge said first electrically conductive member into electrical contact with said third electrically conductive member when in an intact state, said electrolytically erodable junction configured to allow complete physical detachment between said implant and said core wire upon electrolytic erosion of said electrolytically erodable junction to result in a detached state, the transition between said intact state and said detached state being caused by application of a potential difference between said first electrically conductive member and said second electrically conductive member, said potential difference being large enough to cause electrolytic erosion of said electrolytically erodable junction when said junction is disposed in a body fluid.

10. The wire assembly of claim 9 wherein the proximal end of said third electrically conductive member has a contact geometry configuration, said contact geometry configuration comprising a flat surface, said flat surface being perpendicular to the longitudinal axis of said core wire and being designed to physically contact a portion of said first electrically conductive member when said electrolytically erodable junction is in said intact state and a charged electrolysis state.

11. The wire assembly of claim 9 wherein proximal end of said third electrically conductive member has a contact geometry configuration, said contact geometry configuration comprising a socket, said socket being designed to releasably receive and partially surround a portion of said first electrically conductive member when said electrolytically erodable junction is in said intact state and a charged electrolysis state.

12. The wire assembly of claim 9 wherein said third electrically conductive member of said implant comprises a coil.

13. The wire assembly of claim 12 wherein said coil comprises a platinum alloy coil.

14. The wire assembly of claim 9 wherein said electrolytically erodable junction comprises an electrically conductive erodable ring, said electrically conductive erodable ring having an inner diameter and an outer diameter, said ring being in direct electrical contact with said second electrically conductive member and adapted to be in direct electrical contact with surrounding body fluids, said ring being electrically insulated from said first electrically conductive member and said third electrically conductive member, said ring being in direct physical contact with said implant when said electrolytically erodable junction is in said intact state.

15. The wire assembly of claim 14 wherein said electrically conductive erodable ring comprises a metal.

16. The wire assembly of claim 15 wherein said metal is less electrolytically noble than the material which comprises said exposed area of said implant.

17. The wire assembly of claim 14 wherein the electrolytically erodable junction additionally comprises a ring electrically insulating outer layer, said ring electrically insulating outer layer having a score therethrough, said score being configured to expose a discrete area of said electrically conductive erodable ring to surrounding body fluids.

18. The wire assembly of claim 17 wherein said score is produced by laser scoring through the ring electrically insulating outer layer.

19. The wire assembly of claim 17 wherein said ring electrically insulating outer layer comprises materials selected from the group consisting of polyfluorocarbons, polyxylylene, polyethylene, polypropylene, polyurethane, polyimides, and silicone polymers.

20. The wire assembly of claim 19 wherein said ring electrically insulating outer layer comprises a polyfluorocarbon.

21. The wire assembly of claim 20 wherein said ring electrically insulating outer layer comprises a polytetrafluoroethylene.

22. The wire assembly of claim 19 wherein said ring electrically insulating outer layer comprises a polyxylylene.

23. The wire assembly of claim 9 wherein the potential difference applied between said first electrically conductive member and said second electrically conductive member is at least 2 volts.

24. The wire assembly of claim 9 wherein the potential difference applied between said first electrically conductive member and said second electrically conductive member is at least 4 volts.

25. The wire assembly of claim 9 wherein said first electrically conductive member and said second electrically conductive member are electrically insulated from each other and are adapted to be electrically insulated from surrounding body fluids by a first electrically insulating member, said first electrically insulating member having two separate lumens configured to house said first electrically conductive member and said second electrically conductive member.

26. The wire assembly of claim 9 additionally comprising a first electrically insulating member and a second electrically insulating member, said first electrically insulating member being configured to directly contact both said first electrically conductive member and said second electrically conductive member and to electrically insulate them from each other, said second electrically insulating member configured to directly contact said second electrically conductive member and to electrically insulate said second electrically conductive member from surrounding body fluids.

27. The wire assembly of claim 26 wherein said first electrically insulating member surrounds said first electrically conductive member.

28. The wire assembly of claim 27 wherein said second electrically conductive member at least partially surrounds said first electrically insulating member.

29. The wire assembly of claim 28 wherein both of said first electrically insulating member and said second electrically insulating member are generally tubular in shape.

30. The wire assembly of claim 29 wherein said second electrically conductive member comprises a wire which is situated between said first electrically insulating member and said second electrically insulating member, said wire being a single strand extending from the proximal end of said core wire to the distal end, wherein said wire forms electrical contact with said electrolytically erodable junction.

31. A wire assembly for use in formation of an occlusion in a body cavity and suitable for delivery to said body cavity using a catheter comprising:

a composite core wire, said composite core wire having a longitudinal axis, a proximal end, and a distal end, a first electrically conductive member, a second electrically conductive member, and a first electrically insulating member, said first electrically insulating member configured to directly contact both said first electrically conductive member and said second electrically conductive member, to electrically insulate them from each other, and to electrically insulate said first electrically conductive member from surrounding body fluids, and

an implant having a proximal end and a distal end, and

an electrolytically erodable junction, said electrolytically erodable junction being configured to releasably attach the proximal end of said implant to the distal end of said composite core wire when in an intact state, and being configured to allow complete physical detachment between said implant and said core wire upon electrolytic erosion of said electrolytically erodable junction to result in a detached state, the transition between said intact state and said detached state being caused by application of a potential difference between said first electrically conductive member and said second electrically conductive member, said potential difference being large enough to cause electrolytic erosion of said electrolytically erodable junction in a body fluid.

32. The wire assembly of claim 31 wherein said implant comprises a coil.

33. The wire assembly of claim 32 wherein said coil comprises a platinum alloy coil.

34. The wire assembly of claim 31 wherein said electrolytically erodable junction comprises an extension of said first electrically conductive member and said first electrically insulating member wherein said first electrically insulating member has a score therethrough which is configured to allow a discrete area of said first electrically conductive member to establish direct electrical contact with surrounding body fluids.

35. The wire assembly of claim 34 wherein said score is produced by laser scoring through the first electrically insulating member.

36. The wire assembly of claim 34 wherein said first electrically insulating member comprises materials selected from the group consisting of polyfluorocarbons, polyxylylene, polyethylene, polypropylene, polyurethane, polyimides, and silicone polymers.

37. The wire assembly of claim 36 wherein said first electrically insulating member comprises a polyfluorocarbon.

38. The wire assembly of claim 37 wherein said first electrically insulating member comprises a polytetrafluoroethylene.

39. The wire assembly of claim 36 wherein said first electrically insulating member comprises a polyxylylene.

40. The wire assembly of claim 31 wherein the potential difference applied between said first electrically conductive member and said second electrically conductive member is at least 2 volts.

41. The wire assembly of claim 31 wherein the potential difference applied between said first electrically conductive member and said second electrically conductive member is at least 4 volts.

42. The wire assembly of claim 31 wherein said first electrically insulating member surrounds said first electrically conductive member.

43. The wire assembly of claim 42 wherein said second electrically conductive member at least partially surrounds said first electrically insulating member.

44. The wire assembly of claim 43 wherein said first electrically insulating member is generally tubular in shape.

45. The wire assembly of claim 44 wherein said second electrically conductive member comprises a wire which is mounted upon said first electrically insulating member, said wire being a single strand extending from the proximal end of said core wire to the distal end and culminating in a circumferential loop around said distal end.