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Implantable enzyme-based monitoring systems adapted for long term use

  • US 6,081,736 A
  • Filed: 10/20/1997
  • Issued: 06/27/2000
  • Est. Priority Date: 10/20/1997
  • Status: Expired due to Term
First Claim
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1. An implantable monitoring system comprising an enzyme solution and a reservoir, within the monitoring system, for replenishing the enzyme system;

  • further comprising a sensor assembly for sensing a concentration of a substance being monitored;

    wherein said sensor assembly includes a plurality of electrodes on a first side of a substrate and at least one hermetically sealed microprocessor on a second side of the substrate; and

    further comprising hermetically sealed and electrically insulated conductive pathways from the at least one microprocessor to the plurality of electrodes;

    further comprising said electrode assembly bathed in an electrolyte solution;

    further comprising hermetically sealed and electrically insulated leads to a command center that supplies electrical power to the sensor assembly.

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