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High drug:lipid formulations of liposomal-antineoplastic agents

  • US 6,083,530 A
  • Filed: 05/26/1998
  • Issued: 07/04/2000
  • Est. Priority Date: 03/05/1987
  • Status: Expired due to Term
First Claim
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1. A composition comprising:

  • (i) liposomes which comprise an ionizable basic antineoplastic agent, an aqueous release inhibiting buffer and a bilayer comprising a lipid; and

    (ii) an aqueous solution external to the liposomes which is basic with respect to the buffer.

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