×

Chemical amplification for the synthesis of patterned arrays

  • US 6,083,697 A
  • Filed: 11/13/1997
  • Issued: 07/04/2000
  • Est. Priority Date: 11/14/1996
  • Status: Expired due to Term
First Claim
Patent Images

1. An apparatus for solid phase chemical synthesis comprising:

  • i) a substrate having one or more synthesis intermediates bound thereon, the one or more synthesis intermediates including a reactive group protected from reaction by a removable protecting group attached by a chemical bond to the one or more synthesis intermediates;

    ii) a radiation sensitive compound or group, said radiation sensitive compound or group producing a catalyst when irradiated, andiii) an autocatalytic compound or group, said autocatalytic compound or group generating a protecting group removing product when said autocatalytic compound is activated by said catalyst,wherein the radiation sensitive compound or group and the autocatalytic compound or group are included in a polymer layer on the substrate and further wherein the radiation sensitive compound or group and the autocatalytic compound or group are nonidentical and wherein the catalyst and autocatalytic compound or group are nonidentical.

View all claims
  • 5 Assignments
Timeline View
Assignment View
    ×
    ×